Publications [#61040] of Roger C. Barr

Papers Published

1. Plonsey, R. and Barr, R.C. and Witkowski, F.X., One-dimensional model of cardiac defibrillation, Med. Biol. Eng. Comput. (UK), vol. 29 no. 5 , pp. 465 - 9
   (last updated on 2007/04/12)

   Abstract:
   The response of a single strand of cardiac cells to a uniform defibrillatory shock assuming steady-state linear conditions is examined. It is argued that the effect of this current is quantitatively described by the induced transmembrane potential even under passive conditions. The characteristics of the single strand are those that would exist if the heart was a system of equivalent parallel pathways from apex to base. It is shown that essentially every cell is both hyperpolarised and depolarised from the shock by an amount proportional to the stimulus intensity and the intercellular junctional resistance. For physiological values of model parameters the evaluated depolarisations are consistent with levels necessary to affect electrophysiological behaviour

   Keywords:
   bioelectric phenomena;biomembranes;cardiology;cellular biophysics;physiological models;