Publications [#61049] of Roger C. Barr

Papers Published

1. Ihara, T. and Barr, R.C., Electrocardiographic inverse solution for ectopic origin of excitation in two-dimensional propagation model, Med. Biol. Eng. Comput. (UK), vol. 32 no. 4 (1994), pp. 41 - 50
   (last updated on 2007/04/12)

   Abstract:
   Inverse calculations were examined that sought the origin of a cardiac ectopic excitation sequence. Cardiac anatomy and its geometric relationships to sites on the body surface were adapted from human cross-sectional images to form a two-dimensional model, which included ventricular muscle and a primitive conduction system. The surrounding volume conductor was modelled in a simplified way as unbounded, homogeneous and isotropic. In a series of tests, one ectopic origin was designated the `true' origin. The ECG for this true origin was compared to ECGs for 197 ectopic `trial' origins, and differences between the wave forms for true versus trial origins were determined. Core issues were the magnitudes of changes in ECG wave forms as a function of the site of origin, whether these changes were sufficient to imply uniqueness, and what spatial resolution might be expected, in the presence of realistic noise levels. For a noise level of 10 μV RMS, the origin of excitation was localised to a single region of the muscle using one wave form from the body surface, with a resolution of 10 mm. The resolution was not improved significantly with a second electrode on the body surface, but was substantially improved with an endocardial electrode

   Keywords:
   electrocardiography;inverse problems;physiological models;