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| Publications [#279893] of Farshid Guilak
Papers Published
- Gimble, JM; Guilak, F; Nuttall, ME; Sathishkumar, S; Vidal, M; Bunnell, BA, In vitro Differentiation Potential of Mesenchymal Stem Cells.,
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, vol. 35 no. 3
(2008),
pp. 228-238, ISSN 1660-3796 [21547120], [doi]
(last updated on 2019/06/30)
Abstract:
SUMMARY: Mesenchymal stem cells (MSCs) represent a class of multipotent progenitor cells that have been isolated from multiple tissue sites. Of these, adipose tissue and bone marrow offer advantages in terms of access, abundance, and the extent of their documentation in the literature. This review focuses on the in vitro differentiation capability of cells derived from adult human tissue. Multiple, independent studies have demonstrated that MSCs can commit to mesodermal (adipocyte, chondrocyte, hematopoietic support, myocyte, osteoblast, tenocyte), ectodermal (epithelial, glial, neural), and endodermal (hepatocyte, islet cell) lineages. The limitations and promises of these studies in the context of tissue engineering are discussed.
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