Publications of Eric J. Toone

Books

  1. Toone, EJ, "Preface"December,, 2011, 78 1.

  2. Toone, EJ, "Advances in Enzymology and Related Areas of Molecular Biology"October,, 2011, 78, 1-548 [doi] [abs].

  3. Toone, EJ, "Advances in Enzymology and Related Areas of Molecular Biology"February,, 2011, 77, 1-418 [doi] [abs].

  4. Toone, EJ, "Advances in Enzymology: And Related Areas of Molecular Biology"May,, 2010, 75, 1-314 [doi] [abs].

  5. Toone, EJ, "Advances in enzymology and related areas of molecular biology", edited by E.J. Toone September,, 2008, 76, 1-272, Wiley-Interscience [doi] [abs].

  6. E.J. Toone, "Advances in Enzymology and Related Areas of Molecular Biology", edited by E.J. Toone , 2007, 75, Wiley-Interscience.

Journal Articles

  1. Zhao, J; Cochrane, CS; Najeeb, J; Gooden, D; Sciandra, C; Fan, P; Lemaitre, N; Newns, K; Nicholas, RA; Guan, Z; Thaden, JT; Fowler, VG; Spasojevic, I; Sebbane, F; Toone, EJ; Duncan, C; Gammans, R; Zhou, P, "Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens.", Sci Transl MedAugust,, 2023, 15(708), eadf5668 [doi] [abs].

  2. Martorana, AM; Moura, ECCM; Sperandeo, P; Di Vincenzo, F; Liang, X; Toone, E; Zhou, P; Polissi, A, "Degradation of Components of the Lpt Transenvelope Machinery Reveals LPS-Dependent Lpt Complex Stability in Escherichia coli.", Front Mol Biosci, 2021, 8, 758228 [doi] [abs].

  3. Lemaître, N; Liang, X; Najeeb, J; Lee, C-J; Titecat, M; Leteurtre, E; Simonet, M; Toone, EJ; Zhou, P; Sebbane, F, "Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC.", mBioJuly,, 2017, 8(4) [doi] [abs].

  4. Titecat, M; Liang, X; Lee, C-J; Charlet, A; Hocquet, D; Lambert, T; Pagès, J-M; Courcol, R; Sebbane, F; Toone, EJ; Zhou, P; Lemaitre, N, "High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors.", J Antimicrob ChemotherOctober,, 2016, 71(10), 2874-2882 [doi] [abs].

  5. Liang, X; Gopalaswamy, R; Navas, F; Toone, EJ; Zhou, P, "A Scalable Synthesis of the Difluoromethyl-allo-threonyl Hydroxamate-Based LpxC Inhibitor LPC-058.", J Org ChemMay,, 2016, 81(10), 4393-4398 [doi] [abs].

  6. Lee, C-J; Liang, X; Wu, Q; Najeeb, J; Zhao, J; Gopalaswamy, R; Titecat, M; Sebbane, F; Lemaitre, N; Toone, EJ; Zhou, P, "Drug design from the cryptic inhibitor envelope.", Nat CommunFebruary,, 2016, 7, 10638 [doi] [abs].

  7. King, JR; Bowers, CM; Toone, EJ, "Specific binding at the cellulose binding module-cellulose interface observed by force spectroscopy.", Langmuir : the ACS journal of surfaces and colloidsMarch,, 2015, 31(11), 3431-3440 [doi] [abs].

  8. Sund, JB; Causey, CP; Wolter, SD; Parker, CB; Stoner, BR; Toone, EJ; Glass, JT, "Diamond surface functionalization with biomimicry - Amine surface tether and thiol moiety for electrochemical sensors", Applied Surface ScienceMay,, 2014, 301, 293-299 [doi] [abs].

  9. Bowers, CM; Zhang, M; Lyubarskaya, Y; Toone, EJ; Tang, C; Shestopalov, AA, "Structural Modifications in Bilayered Molecular Systems Lead to Predictable Changes in Their Electronic Properties", Advanced Materials InterfacesApril,, 2014, 1(2), 1300109-1300109, WILEY [doi] [abs].

  10. Lee, C-J; Liang, X; Gopalaswamy, R; Najeeb, J; Ark, ED; Toone, EJ; Zhou, P, "Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC.", ACS Chem BiolJanuary,, 2014, 9(1), 237-246 [24117400], [doi] [abs].

  11. Sund, JB; Causey, CP; Wolter, SD; Parker, CB; Stoner, BR; Toone, EJ; Glass, JT, "Diamond surface functionalization with biomimicry - Amine surface tether and thiol moiety for electrochemical sensors", Applied Surface Science, 2014, 301, 293-299, Elsevier BV [doi].

  12. Xia, W; Gooden, D; Liu, L; Zhao, S; Soderblom, EJ; Toone, EJ; Beyer, WF; Walder, H; Spector, NL, "Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis.", PLoS One, 2014, 9(2), e88983 [doi] [abs].

  13. Wang, Y; King, JR; Wu, P; Pelzman, DL; Beratan, DN; Toone, EJ, "Correction to "Enthalpic Signature of Methonium Desolvation Revealed in a Synthetic Host-Guest System Based on Cucurbit[7]uril".", J Am Chem SocNovember,, 2013, 135(46), 17650 [24215303], [doi].

  14. Liang, X; Lee, C-J; Zhao, J; Toone, EJ; Zhou, P, "Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors.", J Med ChemSeptember,, 2013, 56(17), 6954-6966 [23914798], [doi] [abs].

  15. Grant, GA; Hankinson, T; Muh, C; Dumont, A, "The 62nd Annual Meeting of the Congress of Neurological Surgeons was held in Chicago, Illinois from October 6-10, 2012. Preface.", NeurosurgeryAugust,, 2013, 60 Suppl 1, v [doi].

  16. Toone, E; de Winde, H, "Energy biotechnology in 2013: advanced technology development for breakthroughs in fuels and chemicals production.", Current opinion in biotechnologyJune,, 2013, 24(3), 367-368 [doi].

  17. Bowers, CM; Carlson, DA; Rivera, M; Clark, RL; Toone, EJ, "Effect of compressive force on unbinding specific protein-ligand complexes with force spectroscopy.", The journal of physical chemistry. BMay,, 2013, 117(17), 4755-4762 [23537272], [doi] [abs].

  18. Wang, Y; King, JR; Wu, P; Pelzman, DL; Beratan, DN; Toone, EJ, "Enthalpic signature of methonium desolvation revealed in a synthetic host-guest system based on cucurbit[7]uril.", Journal of the American Chemical SocietyApril,, 2013, 135(16), 6084-6091 [23510488], [doi] [abs].

  19. Bowers, CM; Carlson, DA; Shestopalov, AA; Clark, RL; Toone, EJ, "A general and efficient cantilever functionalization technique for AFM molecular recognition studies.", BiopolymersOctober,, 2012, 97(10), 761-765 [22806495], [doi] [abs].

  20. Wilfong, EM; Du, Y; Toone, EJ, "An enthalpic basis of additivity in biphenyl hydroxamic acid ligands for stromelysin-1.", Bioorganic & medicinal chemistry lettersOctober,, 2012, 22(20), 6521-6524 [22985855], [doi] [abs].

  21. Bowers, CM; Shestopalov, AA; Clark, RL; Toone, EJ, "Multicomponent patterning of indium tin oxide.", ACS applied materials & interfacesAugust,, 2012, 4(8), 3932-3937 [22834789], [doi] [abs].

  22. Cheriyan, M; Toone, EJ; Fierke, CA, "Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates.", BiochemistryFebruary,, 2012, 51(8), 1658-1668 [22316217], [doi] [abs].

  23. Coombs, GS; Schmitt, AA; Canning, CA; Alok, A; Low, ICC; Banerjee, N; Kaur, S; Utomo, V; Jones, CM; Pervaiz, S; Toone, EJ; Virshup, DM, "Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.", OncogeneJanuary,, 2012, 31(2), 213-225 [21666721], [doi] [abs].

  24. Smith, AD; Badlani, GH; Preminger, GM; Kavoussi, LR, "Preface", Smith's Textbook of Endourology: 3rd EditionJanuary,, 2012, 1-2(6), xiii, WILEY-BLACKWELL [doi].

  25. Yamazaki, A; Li, J; Zeng, Q; Khokhani, D; Hutchins, WC; Yost, AC; Biddle, E; Toone, EJ; Chen, X; Yang, C-H, "Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system.", Antimicrobial agents and chemotherapyJanuary,, 2012, 56(1), 36-43 [21968370], [doi] [abs].

  26. Bowers, CM; Toone, EJ; Clark, RL; Shestopalov, AA, "Soft lithographic functionalization and patterning oxide-free silicon and germanium.", Journal of visualized experiments : JoVEDecember,, 2011(58), 3478 [22214997], [doi] [abs].

  27. Cheriyan, M; Walters, MJ; Kang, BD; Anzaldi, LL; Toone, EJ; Fierke, CA, "Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate.", Bioorganic & medicinal chemistryNovember,, 2011, 19(21), 6447-6453 [21944547], [doi] [abs].

  28. Lund, LN; Christensen, T; Toone, E; Houen, G; Staby, A; St Hilaire, PM, "Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry.", Journal of molecular recognition : JMRNovember,, 2011, 24(6), 945-952 [doi] [abs].

  29. Wilfong, EM; Kogiso, Y; Muthukrishnan, S; Kowatz, T; Du, Y; Bowie, A; Naismith, JH; Hadad, CM; Toone, EJ; Gustafson, TL, "A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model.", Journal of the American Chemical SocietyAugust,, 2011, 133(30), 11515-11523 [21692482], [doi] [abs].

  30. Nguyen, BD; Cunningham, D; Liang, X; Chen, X; Toone, EJ; Raetz, CRH; Zhou, P; Valdivia, RH, "Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis.", Proc Natl Acad Sci U S AJune,, 2011, 108(25), 10284-10289 [21628561], [doi] [abs].

  31. Morris, CJ; Shestopalov, AA; Gold, BH; Clark, RL; Toone, EJ, "Patterning NHS-terminated SAMs on germanium.", Langmuir : the ACS journal of surfaces and colloidsMay,, 2011, 27(10), 6486-6489 [21504221], [doi] [abs].

  32. Shestopalov, AA; Morris, CJ; Vogen, BN; Hoertz, A; Clark, RL; Toone, EJ, "Soft-lithographic approach to functionalization and nanopatterning oxide-free silicon.", Langmuir : the ACS journal of surfaces and colloidsMay,, 2011, 27(10), 6478-6485 [21520913], [doi] [abs].

  33. Hwang, S; Schmitt, AA; Luteran, AE; Toone, EJ; McCafferty, DG, "Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST.", BiochemistryFebruary,, 2011, 50(4), 546-557 [21142040], [doi] [abs].

  34. Lee, C-J; Liang, X; Chen, X; Zeng, D; Joo, SH; Chung, HS; Barb, AW; Swanson, SM; Nicholas, RA; Li, Y; Toone, EJ; Raetz, CRH; Zhou, P, "Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.", Chem BiolJanuary,, 2011, 18(1), 38-47 [21167751], [doi] [abs].

  35. Liang, X; Lee, C-J; Chen, X; Chung, HS; Zeng, D; Raetz, CRH; Li, Y; Zhou, P; Toone, EJ, "Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold.", Bioorg Med ChemJanuary,, 2011, 19(2), 852-860 [21194954], [doi] [abs].

  36. Toone, EJ, "Bacterial infection remains a leading cause of death in both Western and developing world. Preface.", Advances in enzymology and related areas of molecular biologyJanuary,, 2011, 77, xi-xiii [21692365].

  37. Toone, EJ, "Advances in enzymology and related areas of molecular biology. Preface.", Advances in enzymology and related areas of molecular biologyJanuary,, 2011, 78, ix-xi [22220470].

  38. Colomer, J; Schmitt, AA; Toone, EJ; Means, AR, "Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist.", BiochemistryMay,, 2010, 49(19), 4244-4254 [20392081], [doi] [abs].

  39. Shestopalov, AA; Clark, RL; Toone, EJ, "Catalytic microcontact printing on chemically functionalized H-terminated silicon.", Langmuir : the ACS journal of surfaces and colloidsFebruary,, 2010, 26(3), 1449-1451 [19950970], [doi] [abs].

  40. Toone, EJ, "Forcing a closer look", BiopolymersJanuary,, 2010, 93(1), iii-iv, WILEY [doi].

  41. Shestopalov, AA; Clark, RL; Toone, EJ, "Inkless microcontact printing on SAMs of Boc- and TBS-protected thiols.", Nano lettersJanuary,, 2010, 10(1), 43-46 [19950928], [doi] [abs].

  42. Wilfong, EM; Locklear, U; Toone, EJ, "A single step purification for autolytic zinc proteinases.", Bioorganic & medicinal chemistry lettersJanuary,, 2010, 20(1), 280-282 [19942433], [doi] [abs].

  43. Rivera, M; Morris, C; Carlson, D; Toone, EJ; Cole, DG; Clark, RL, "Minimizing tip-sample contact force in automated atomic force microscope based force spectroscopy", Proceedings of the ASME Design Engineering Technical ConferenceDecember,, 2009, 6, 731-736 [doi] [abs].

  44. Gao, W; Liu, W; Mackay, JA; Zalutsky, MR; Toone, EJ; Chilkoti, A, "In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics.", Proc Natl Acad Sci U S ASeptember,, 2009, 106(36), 15231-15236 [19706892], [doi] [abs].

  45. Arnold, JJ; Choksi, Y; Chen, X; Shimazaki, A; Hatten, J; Toone, EJ; Epstein, DL; Challa, P, "Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits.", J Ocul Pharmacol TherJune,, 2009, 25(3), 179-186 [19456251], [doi] [abs].

  46. Chakrapani, H; Bartberger, MD; Toone, EJ, "C-nitroso donors of nitric oxide.", The Journal of organic chemistryFebruary,, 2009, 74(4), 1450-1453 [19146387], [doi] [abs].

  47. Toone, EJ, "Advances in enzymology and related areas of molecular biology. Preface.", Advances in enzymology and related areas of molecular biologyJanuary,, 2009, 76, ix-x [18990826].

  48. Williams, GJ; Thorson, JS, "Natural product glycosyltransferases: properties and applications.", Advances in enzymology and related areas of molecular biologyJanuary,, 2009, 76, 55-119 [doi].

  49. Lai, T-S; Liu, Y; Tucker, T; Daniel, KR; Sane, DC; Toone, E; Burke, JR; Strittmatter, WJ; Greenberg, CS, "Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries.", Chem BiolSeptember,, 2008, 15(9), 969-978 [18804034], [doi] [abs].

  50. Walters, MJ; Srikannathasan, V; McEwan, AR; Naismith, JH; Fierke, CA; Toone, EJ, "Characterization and crystal structure of Escherichia coli KDPGal aldolase.", Bioorganic & medicinal chemistryJanuary,, 2008, 16(2), 710-720 [17981470], [doi] [abs].

  51. Shestopalov, AA; Clark, RL; Toone, EJ, "Inkless microcontact printing on self-assembled monolayers of fmoc-protected aminothiols.", Journal of the American Chemical SocietyNovember,, 2007, 129(45), 13818-13819 [17949005], [doi].

  52. Cheriyan, M; Toone, EJ; Fierke, CA, "Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates.", Protein science : a publication of the Protein SocietyNovember,, 2007, 16(11), 2368-2377 [17962400], [doi] [abs].

  53. Snyder, PW; Johannes, MS; Vogen, BN; Clark, RL; Toone, EJ, "Biocatalytic microcontact printing.", The Journal of organic chemistrySeptember,, 2007, 72(19), 7459-7461 [17705546], [doi] [abs].

  54. Matsuoka, K; Goshu, Y; Takezawa, Y; Mori, T; Sakamoto, JI; Yamada, A; Onaga, T; Koyama, T; Hatano, K; Snyder, PW; Toone, EJ; Terunuma, D, "Practical synthesis of fully protected globotriaose and its glycopolymers", Carbohydrate PolymersJune,, 2007, 69(2), 326-335, Elsevier BV [doi] [abs].

  55. Snyder, PW; Lee, G; Marszalek, PE; Clark, RL; Toone, EJ, "A stochastic, cantilever approach to the evaluation of solution phase thermodynamic quantities.", Proceedings of the National Academy of Sciences of the United States of AmericaFebruary,, 2007, 104(8), 2579-2584 [17307881], [doi] [abs].

  56. Sidebotham, D; Mckee, A; Gillham, M; Levy, JH, "Preface", Cardiothoracic Critical CareJanuary,, 2007, ix-ix, Elsevier [doi].

  57. Walters, MJ; Toone, EJ, "Pyruvate aldolases in chiral carbon-carbon bond formation.", Nature protocolsJanuary,, 2007, 2(7), 1825-1830 [17641651], [doi] [abs].

  58. Snyder, P. W.; Lee, G.; Marszalek, P. E.; Clark, R. L.; Toone, E. J., "Quantitative determination of analytes by force microscopy", Proc. Natl. Acad. Sci. USA, 2007(104), 2579-2584.

  59. Cheryian, M; Toone, EJ; Fierke, CA, "Substrate specificity of the electrophilic binding site of KDPG aldolase is altered by mutagenesis", Bioorg. Med. Chem., 2007.

  60. Perry, JL; Goldsmith, MR; Williams, TR; Radack, KP; Christensen, T; Gorham, J; Pasquinelli, MA; Toone, EJ; Beratan, DN; Simon, JD, "Binding of warfarin influences the acid-base equilibrium of H242 in sudlow site I of human serum albumin.", Photochemistry and photobiologySeptember,, 2006, 82(5), 1365-1369 [16563025], [doi] [abs].

  61. Fullerton, SWB; Griffiths, JS; Merkel, AB; Cheriyan, M; Wymer, NJ; Hutchins, MJ; Fierke, CA; Toone, EJ; Naismith, JH, "Mechanism of the Class I KDPG aldolase.", Bioorganic & medicinal chemistryMay,, 2006, 14(9), 3002-3010 (IN PRESS.) [16403639], [doi] [abs].

  62. Pamula, VK; Srinivasan, V; Chakrapani, H; Fair, RB; Toone, EJ, "A droplet-based lab-on-a-chip for colorimetric detection of nitroaromatic explosives", Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)October,, 2005, 722-725, IEEE [doi] [abs].

  63. Zhao, Y-L; McCarren, PR; Houk, KN; Choi, BY; Toone, EJ, "Nitrosonium-catalyzed decomposition of s-nitrosothiols in solution: a theoretical and experimental study.", Journal of the American Chemical SocietyAugust,, 2005, 127(31), 10917-10924 [16076198], [doi] [abs].

  64. Winter-Vann, AM; Baron, RA; Wong, W; dela Cruz, J; York, JD; Gooden, DM; Bergo, MO; Young, SG; Toone, EJ; Casey, PJ, "A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.", Proc Natl Acad Sci U S AMarch,, 2005, 102(12), 4336-4341 [15784746], [doi] [abs].

  65. Mori, T; Hatano, K; Matsuoka, K; Esumi, Y; Toone, EJ; Terunuma, D, "Synthesis of carbosilane dendrimers having peripheral mannose and mannobiose", TetrahedronMarch,, 2005, 61(11), 2751-2760, Elsevier BV [doi] [abs].

  66. Gooden, DM; Chakrapani, H; Toone, EJ, "C-nitroso compounds: synthesis, physicochemical properties and biological activities.", Current topics in medicinal chemistryJanuary,, 2005, 5(7), 687-705 [16101429], [doi] [abs].

  67. Snyder, PW; Lee, G; Marszalke, PE; Clark, RL; Toone, EJ, "Quantitative determination of analytes by force microscopy", J. Am. Chem. Soc., 2005.

  68. Griffiths, JS; Cheriyan, M; Corbell, JB; Pocivavsek, L; Fierke, CA; Toone, EJ, "A bacterial selection for the directed evolution of pyruvate aldolases.", Bioorganic & medicinal chemistryAugust,, 2004, 12(15), 4067-4074 [15246084], [doi] [abs].

  69. Perry, JL; Christensen, T; Goldsmith, MR; Toone, EJ; Beratan, DN; Simon, JD, "Binding of ochratoxin a to human serum albumin stabilized by a protein-ligand ion pair", Journal of Physical Chemistry BAugust,, 2003, 107(31), 7884-7888, American Chemical Society (ACS) [doi] [abs].

  70. Debenham, SD; Snyder, PW; Toone, EJ, "Solid-phase synthesis for the identification of high-affinity bivalent lectin ligands.", The Journal of organic chemistryJuly,, 2003, 68(15), 5805-5811 [12868911], [doi] [abs].

  71. Houk, KN; Hietbrink, BN; Bartberger, MD; McCarren, PR; Choi, BY; Voyksner, RD; Stamler, JS; Toone, EJ, "Nitroxyl disulfides, novel intermediates in transnitrosation reactions.", Journal of the American Chemical SocietyJune,, 2003, 125(23), 6972-6976 [12783550], [doi] [abs].

  72. Christensen, T; Gooden, DM; Kung, JE; Toone, EJ, "Additivity and the physical basis of multivalency effects: a thermodynamic investigation of the calcium EDTA interaction.", Journal of the American Chemical SocietyJune,, 2003, 125(24), 7357-7366 [12797810], [doi] [abs].

  73. Christensen, T; Toone, EJ, "Calorimetric evaluation of protein-carbohydrate affinities.", Methods in enzymologyJanuary,, 2003, 362, 486-504 [12968383], [doi].

  74. Lundquist, JJ; Kiburz, BM; Wu, JK; Gibbs, KD; Toone, EJ, "Towards high affinity carbohydrate-binding proteins: Directed evolution of murine galectin-3", Canadian Journal of ChemistryDecember,, 2002, 80(8), 999-1009, Canadian Science Publishing [doi] [abs].

  75. Stamler, JS; Toone, EJ, "The decomposition of thionitrites.", Current opinion in chemical biologyDecember,, 2002, 6(6), 779-785 [12470731], [doi] [abs].

  76. Choi, BY; Voyksner, RD; Toone, EJ, "Analysis of S-nitrosothiol decomposition", Proceedings 50th ASMS Conference on Mass Spectrometry and Allied TopicsDecember,, 2002, 799-800 [abs].

  77. Griffiths, JS; Wymer, NJ; Njolito, E; Niranjanakumari, S; Fierke, CA; Toone, EJ, "Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase.", Bioorganic & medicinal chemistryMarch,, 2002, 10(3), 545-550 [11814840], [doi] [abs].

  78. Lundquist, JJ; Toone, EJ, "The cluster glycoside effect.", Chemical reviewsFebruary,, 2002, 102(2), 555-578 [11841254], [doi].

  79. Bartberger, MD; Mannion, JD; Powell, SC; Stamler, JS; Houk, KN; Toone, EJ, "S-N dissociation energies of S-nitrosothiols: on the origins of nitrosothiol decomposition rates.", Journal of the American Chemical SocietySeptember,, 2001, 123(36), 8868-8869 [11535101], [doi].

  80. Moya, MP; Gow, AJ; McMahon, TJ; Toone, EJ; Cheifetz, IM; Goldberg, RN; Stamler, JS, "S-nitrosothiol repletion by an inhaled gas regulates pulmonary function.", Proc Natl Acad Sci U S AMay,, 2001, 98(10), 5792-5797 [11320213], [doi] [abs].

  81. DiTusa, CA; Christensen, T; McCall, KA; Fierke, CA; Toone, EJ, "Thermodynamics of metal ion binding. 1. Metal ion binding by wild-type carbonic anhydrase.", BiochemistryMay,, 2001, 40(18), 5338-5344 [11330996], [doi] [abs].

  82. DiTusa, CA; McCall, KA; Christensen, T; Mahapatro, M; Fierke, CA; Toone, EJ, "Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants.", BiochemistryMay,, 2001, 40(18), 5345-5351 [11330997], [doi] [abs].

  83. Wymer, N; Buchanan, LV; Henderson, D; Mehta, N; Botting, CH; Pocivavsek, L; Fierke, CA; Toone, EJ; Naismith, JH, "Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli.", Structure (London, England : 1993)January,, 2001, 9(1), 1-9 [11342129], [doi] [abs].

  84. Mehta, N.; Buchanan, L. V.; Pocivavsek, L.; Niranfanakumari, S.; Fierke, C. A.; Toone, E. J.; Naismith, J. H., "Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldonlase from Escherichia coli.", Structure, 2001, 9, 1-9.

  85. Ditusa, CA; Fierke, CA; Toone, EJ, "Thermodynamics of Metal Ion Bonding. II. Metal Ion Binding by Mutated Carbonic Anhydrases.", Biochemistry, 2001, 40(18), 5345-5351 [11330997] [abs].

  86. Lundquist, JJ; Debenham, SD; Toone, EJ, "Multivalency effects in protein--carbohydrate interaction: the binding of the Shiga-like toxin 1 binding subunit to multivalent C-linked glycopeptides.", The Journal of organic chemistryDecember,, 2000, 65(24), 8245-8250 [11101380], [doi] [abs].

  87. Bartberger, MD; Houk, KN; Powell, SC; Mannion, JD; Lo, KY; Stamler, JS; Toone, EJ, "Theory, spectroscopy, and crystallographic analysis of S-nitrosothiols: Conformational distribution dictates spectroscopic behavior [7]", Journal of the American Chemical SocietyJune,, 2000, 122(24), 5889-5890, American Chemical Society (ACS) [doi].

  88. Trzaska, SM; Toone, EJ; Crumbliss, AL, "Microcalorimetric determination of thermodynamic parameters for ionophore-siderophore host-guest complex formation.", Inorganic chemistryMarch,, 2000, 39(6), 1071-1075 [12526393], [doi] [abs].

  89. Debenham, SD; Toone, EJ, "Regioselective reduction of 4,6-O-benzylidenes using triethylsilane and BF3.Et2O", Tetrahedron AsymmetryFebruary,, 2000, 11(2), 385-387, Elsevier BV [doi] [abs].

  90. Wymer, N; Toone, EJ, "Enzyme-catalyzed synthesis of carbohydrates.", Current opinion in chemical biologyFebruary,, 2000, 4(1), 110-119 [10679369], [doi] [abs].

  91. Corbell, JB; Lundquist, JJ; Toone, EJ, "A comparison of biological and calorimetric analyses of multivalent glycodendrimer ligands for concanavalin A", Tetrahedron AsymmetryJanuary,, 2000, 11(1), 95-111, Elsevier BV [doi] [abs].

  92. Bartberger, MD; Houk, KN; Powell, S; Mannion, J; Lo, KYK; Stamler, JS; Toone, EJ, "Nuclear Magnetic Resonance and Visible Spectroscopy of S-Nitrosothiols. Conformational Distribution Dictates Spectroscopic Behavior.", J. Am. Chem. Soc., 2000, 122(24), 5889-5890 [doi].

  93. Wymer, N; Toone, EJ, "Enzymatic Carbohydrate Synthesis", Current Opinion in Chemical Biology, 2000, 4, 110-119.

  94. Debenham, S; Toone, EJ, "A Facile Method for the Reductive Deprotection of Carbohydrate Benzylidene Protecting Groups.", Tetrahedron Asymm., 2000, 385-387.

  95. Lundquist, JJ; Debenham, SD; Toone, EJ, "Calorimetric and Biological Evaluation of Shigalike Toxin1 Binding to Multivalent C-Linked Glycopeptides", J. Org. Chem., 2000, 65(24), 8245-8250 [11101380] [abs].

  96. Corbell, JB; Lundquist, JJ; Toone, EJ, "Biological and Calorimetric Analysis of Multivalent Glycodendrimers Ligands for Concanavalin A.", Tetrahedron Asymm., 2000, 11(1), 95-111 [doi] [abs].

  97. Debenham, SD; Cossrow, J; Toone, EJ, "Synthesis of α- and β-carbon-linked serine analogues of the P(k) trisaccharide", Journal of Organic ChemistryDecember,, 1999, 64(25), 9153-9163, American Chemical Society (ACS) [doi] [abs].

  98. Dimick, SM; Powell, SC; McMahon, SA; Moothoo, DN; Naismith, JH; Toone, EJ, "On the meaning of affinity: Cluster glycoside effects and concanavalin A", Journal of the American Chemical SocietyNovember,, 1999, 121(44), 10286-10296, American Chemical Society (ACS) [doi] [abs].

  99. Buchanan, LV; Mehta, N; Pocivavsek, L; Niranjanakumari, S; Toone, EJ; Naismith, JH, "Initiating a structural study of 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli.", Acta crystallographica. Section D, Biological crystallographyNovember,, 1999, 55(Pt 11), 1946-1948 [doi] [abs].

  100. Wymer, N; Buchanan, LV; Mehta, N; Pocivavsek, L; Nirjanakumari, S; Toone, EJ; Naismith, JH, "Initiating a Structural Study of KDPG Aldolase from Escherichia coli", Acta Cryst., 1999, D55(11), 1946-1948 [doi] [abs].

  101. Cotterill, IC; Henderson, DP; Shelton, MC; Toone, EJ, "The synthetic utility of KDPGal aldolase", Journal of Molecular Catalysis - B EnzymaticSeptember,, 1998, 5(1-4), 103-111, Elsevier BV [doi] [abs].

  102. Moothoo, DN; McMahon, SA; Dimick, SM; Toone, EJ; Naismith, JH, "Crystallization of succinylated concanavalin A bound to a synthetic bivalent ligand and preliminary structural analysis.", Acta crystallographica. Section D, Biological crystallographySeptember,, 1998, 54(Pt 5), 1023-1025 [9757127], [doi] [abs].

  103. Cotterill, IC; Shelton, MC; Machemer, DEW; Henderson, DP; Toone, EJ, "Effect of phosphorylation on the reaction rate of unnatural electrophiles with 2-keto-3-deoxy-6-phosphogluconate aldolase", Journal of the Chemical Society - Perkin Transactions 1April,, 1998(7), 1335-1341, Royal Society of Chemistry (RSC) [doi] [abs].

  104. Henderson, DP; Cotterill, IC; Shelton, MC; Toone, EJ, "2-Keto-3-deoxy-6-phosphogalactonate Aldolase as a Catalyst for Stereocontrolled Carbon-Carbon Bond Formation", Journal of Organic ChemistryFebruary,, 1998, 63(4), 906-907, American Chemical Society (ACS) [doi].

  105. Cotterill, IC; Shelton, MC; Henderson, DF; Toone, EJ, "Phosphate as Both a Activating and Protecting Group in Aldolase-Based Syntheses", J. Chem. Soc. Perkin Trans. I, 1998, 7, 1335-1342.

  106. Henderson, DP; Shelton, MC; Cotterill, IC; Toone, EJ, "Stereospecific Preparation of the N-Terminal Amino Acid Moiety of Nikkomycins K(X) and K(Z) via a Multiple Enzyme Synthesis.", The Journal of organic chemistryNovember,, 1997, 62(23), 7910-7911 [11671888], [doi].

  107. Stamler, JS; Toone, EJ; Lipton, SA; Sucher, NJ, "(S)NO signals: translocation, regulation, and a consensus motif.", NeuronMay,, 1997, 18(5), 691-696 [9182795], [doi].

  108. Harris, SL; Craig, L; Mehroke, JS; Rashed, M; Zwick, MB; Kenar, K; Toone, EJ; Greenspan, N; Auzanneau, FI; Marino-Albernas, JR; Pinto, BM; Scott, JK, "Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies.", Proceedings of the National Academy of Sciences of the United States of AmericaMarch,, 1997, 94(6), 2454-2459 [9122216], [doi] [abs].

  109. Debenham, SD; Debenham, JS; Burk, MJ; Toone, EJ, "Synthesis of carbon-linked glycopeptides through catalytic asymmetric hydrogenation", Journal of the American Chemical SocietyJanuary,, 1997, 119(41), 9897-9898, American Chemical Society (ACS) [doi].

  110. Stamler, JS; Toone, EJ; Lipton, S; Sucher, N, "(S)NO Signals: A Consensus Motif", Neuron, 1997, 18(5), 691 [9182795].

  111. Oas, TG; Toone, EJ, "Thermodynamic Solvent Isotope Effects and Molecular Hydorphobicity", Adv. Biophys. Chem., 1997, 6, 1-52.

  112. Gupta, D; Oscarson, S; Raju, TS; Stanley, P; Toone, EJ; Brewer, CF, "A comparison of the fine saccharide-binding specificity of Dioclea grandiflora lectin and concanavalin A.", European journal of biochemistryDecember,, 1996, 242(2), 320-326 [8973650], [doi] [abs].

  113. Shelton, MC; Cotterill, IC; Novak, STA; Poonawala, RM; Sudarshan, S; Toone, EJ, "2-keto-3-deoxy-6-phosphogluconate aldolases as catalysts for stereocontrolled carbon-carbon bond formation", Journal of the American Chemical SocietyDecember,, 1996, 118(9), X-2125 [abs].

  114. Chervenak, MC; Toone, EJ, "Analysis of the binding specificities of oligomannoside-binding proteins using methylated monosaccharides.", Bioorganic & medicinal chemistryNovember,, 1996, 4(11), 1963-1977 [9007280], [doi] [abs].

  115. Weatherman, RV; Mortell, KH; Chervenak, M; Kiessling, LL; Toone, EJ, "Specificity of C-glycoside complexation by mannose/glucose specific lectins.", BiochemistryMarch,, 1996, 35(11), 3619-3624 [8639514], [doi] [abs].

  116. Clark, C; Bast, D; Sharp, AM; St Hilaire, PM; Agha, R; Stein, PE; Toone, EJ; Read, RJ; Brunton, JL, "Phenylalanine 30 plays an important role in receptor binding of verotoxin-1.", Molecular microbiologyFebruary,, 1996, 19(4), 891-899 [8820657], [doi] [abs].

  117. Shelton, MC; Cotterill, IC; Novak, STA; Poonawala, RM; Sudarshan, S; Toone, EJ, "2-Keto-3-deoxy-6-phosphogluconate aldolases as catalysts for stereocontrolled carbon-carbon bond formation", Journal of the American Chemical SocietyJanuary,, 1996, 118(9), 2117-2125, American Chemical Society (ACS) [doi] [abs].

  118. Shelton, MC; Cotterill, IC; Novak, STA; Poonawala, RM; Sudarshan, S; Toone, EJ, "Keto-3-Deoxy-6-Phosphogluconate Aldolases as Catalysts for Stereocontrolled Carbon-Carbon Bond Formation", J. Am. Chem. Soc., 1996, 118(9), 2117-2125 [doi] [abs].

  119. Chervenak, MC; Toone, EJ, "Calorimetric analysis of the binding of lectins with overlapping carbohydrate-binding ligand specificities.", BiochemistryApril,, 1995, 34(16), 5685-5695 [7727428], [doi] [abs].

  120. Chervenak, MC; Toone, EJ, "Corrections. Calorimetric Analysis of the Binding of Lectins with Overlapping Carbohydrate-Binding Ligand Specificities (Biochemistry (1995) 34(16) (5685–5695) (10.1021/bi00016a045))", BiochemistryJanuary,, 1995, 34(24), 7966, American Chemical Society (ACS) [doi].

  121. Isbister, BD; Hilaire, PMS; Toone, EJ, "Spatial Organization versus Total Surface Area as a Predictor of Protein Hydrophobicity. The Hydrophobicity of the Concanavalin A Binding Site†", Journal of the American Chemical SocietyJanuary,, 1995, 117(51), 12877-12878, American Chemical Society (ACS) [doi].

  122. Shelton, MC; Toone, EJ, "Differential dye-ligand chromatography as a general purification protocol for 2-keto-3-deoxy-6-phosphogluconate aldolases", Tetrahedron: AsymmetryJanuary,, 1995, 6(1), 207-211, Elsevier BV [doi] [abs].

  123. St Hilaire, PM; Boyd, MK; Toone, EJ, "Interaction of the Shiga-like toxin type 1 B-subunit with its carbohydrate receptor.", BiochemistryDecember,, 1994, 33(48), 14452-14463 [7981205], [doi] [abs].

  124. Chervenak, MC; Toone, EJ, "A Direct Measure of the Contribution of Solvent Reorganization to the Enthalpy of Binding", Journal of the American Chemical SocietyNovember,, 1994, 116(23), 10533-10539, American Chemical Society (ACS) [doi] [abs].

  125. Simon, SA; Disalvo, EA; Gawrisch, K; Borovyagin, V; Toone, E; Schiffman, SS; Needham, D; McIntosh, TJ, "Increased adhesion between neutral lipid bilayers: interbilayer bridges formed by tannic acid.", Biophys JJune,, 1994, 66(6), 1943-1958 [8075329], [doi] [abs].

  126. Toone, EJ, "Structure and energetics of protein-carbohydrate complexes", edited by Bundle, D.R., Fiezi, T. , Current Opinion in Structural BiologyJanuary,, 1994, 4(5), 719-728, Elsevier BV [doi] [abs].

  127. Simon, SA; Sisalvo, EA; Gawrisch, K; Borovyagin, V; Toone, EJ; Schiffman, SS; Needham, D; McIntosh, TJ, "A Molecular Mechanism for Increasing Adhesion Between Neutral Lipid Membranes: Interbilayer Bridges Formed by Tannic Acid", Biophys. J., 1994, 66, 1943-1957.

  128. Williams, BA; Toone, EJ, "Calorimetric Evaluation of Enzyme Kinetic Parameters", Journal of Organic ChemistryJanuary,, 1993, 58(13), 3507-3510, American Chemical Society (ACS) [doi] [abs].

  129. Williams, BA; Chervenak, MC; Toone, EJ, "Energetics of lectin-carbohydrate binding. A microcalorimetric investigation of concanavalin A-oligomannoside complexation.", The Journal of biological chemistryNovember,, 1992, 267(32), 22907-22911 [1429640], [doi] [abs].

  130. Allen, ST; Heintzelman, GR; Toone, EJ, "Pyruvate Aldolases as Reagents for Stereospecific Aldol Condensation", Journal of Organic ChemistryJanuary,, 1992, 57(2), 426-427, American Chemical Society (ACS) [doi] [abs].

  131. Hamakawa, Y; Matsunami, H, "Preface", Solar Energy MaterialsDecember,, 1991, 23(2-4), 3, Elsevier BV [doi].

  132. Toone, EJ; Simon, ES; Whitesides, GM, "Enzymatic Synthesis of Uridine 5′-Diphosphoglucuronic Acid on a Gram Scale", Journal of Organic ChemistrySeptember,, 1991, 56(19), 5603-5606, American Chemical Society (ACS) [doi] [abs].

  133. Toone, EJ; Jones, JB, "Enzymes in organic synthesis 49. Resolutions of racemic monocyclic esters with pig liver esterase.", Tetrahedron: AsymmetryJanuary,, 1991, 2(3), 207-222, Elsevier BV [doi] [abs].

  134. Toone, EJ; Jones, JB, "Enzymes in organic synthesis 50. Probing the dimensions of the large hydrophobic binding region of the active site of pig liver esterase using substituted aryl malonate substrates", Tetrahedron: AsymmetryJanuary,, 1991, 2(10), 1041-1052, Elsevier BV [doi] [abs].

  135. Toone, E.J.; Whitesides, G.M., "Enzymes as Catalysts in Carbohydrate Synthesis", edited by Bednarski, M.D.; Simn, E.S. , ACS Symposium Series 466, 1991, ACS: Wahsington, D.C..

  136. Toone, EJ; Jones, JB, "Enzymes in Organic Synthesis. 50. Probing the Dimensions of the Large Hydrophobic Binding Region of the Active Site of Pig Liver Esterase Using Substituted Aryl Malonate Substrates", Tetrahedron Asym., 1991, 2(10), 207 [abs].

  137. von der Osten, CH; Gioannetti, C; Barbas, C; Pederson, RL; Wang, YF; Wong, CH; Ozaki, A; Toone, E; Whitesides, GM; Sinskey, AJ, "Molecular cloning of aldolases for synthetic applications.", Enzyme Eng. 10, Annals of the New York Academy of SciencesJanuary,, 1990, 613, 771-775 [doi].

  138. Ozaki, A; Toone, EJ; Whitesides, GM; vonderOsten, CH; Sinskey, AJ, "Overproduction and Substrate Specificity of a Bacterial Fuculose-1-phosphate Aldolase: A New Enzymatic Catalyst for Stereocontrolled Aldol Condensation", Journal of the American Chemical SocietyJanuary,, 1990, 112(12), 4970-4971, American Chemical Society (ACS) [doi].

  139. Toone, EJ; Werth, MJ; Bryan Jones, J, "Active-Site Model for Interpreting and Predicting the Specificity of Pig Liver Esterase", Journal of the American Chemical SocietyJanuary,, 1990, 112(12), 4946-4952 [doi] [abs].

  140. Toone, E.J; Kobori, Y.; Myles, D.C.; Ozaki, A.; Schmid, W.; von der Osten, C.; Sinskey, A.J.; Whitesides, G.M., "Enzymes as Catalysts in Carbohydrate Synthesis", edited by Baldwin, T.O.; Raushel, F.M.; Scott, A.I. , Proceedings of the Texas A&M University IUCCP Eighth Annual Symposium on Chemical Aspects of Enzyme Biotechnology: Fundamentals, March 19-22, 1990, 1990, Plenum: New York.

  141. Toone, E, "Computer Software Reviews", Journal of the American Chemical SocietyMarch,, 1989, 111(5), 1942-1943, American Chemical Society (ACS) [doi].

  142. Simon, ES; Toone, EJ; Ostroff, G; Bednarski, MD; Whitesides, GM, "Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid.", Methods in enzymologyJanuary,, 1989, 179, 275-287 [2560122], [doi].

  143. Toone, EJ; Simon, ES; Bednarski, MD; Whitesides, GM, "Enzyme-catalyzed synthesis of carbohydrates", TetrahedronJanuary,, 1989, 45(17), 5365-5422, Elsevier BV [doi].

  144. Lam, LKP; Brown, CM; Lym, L; Toone, EJ; Jones, JB; Jeso, BD, "Enzymes in organic synthesis. 42. Investigation of the effects of the isozymal composition of pig liver esterase on its stereoselectivity in preparative-scale ester hydrolyses of asymmetric synthetic value", Journal of the American Chemical SocietyJanuary,, 1988, 110(13), 4409-4411, American Chemical Society (ACS) [doi] [abs].

  145. Lemiere, GL; Dommisse, RA; Lepoivre, JA; Alderweireldt, FC; Hiemstra, H; Wynberg, H; Jones, JB; Toone, EJ, "Determination of the Absolute Configuration of Six-Membered-Ring Ketones by 13C NMR", Journal of the American Chemical SocietyMarch,, 1987, 109(5), 1363-1370, American Chemical Society (ACS) [doi] [abs].

  146. Toone, EJ; Jones, JB, "Enzymes in organic synthesis. 40. Evaluation of the enantioselectivity of the pig liver esterase catalyzed hydrolyses of racemic piperidine carboxylic acid esters", Canadian Journal of ChemistryJanuary,, 1987, 65(12), 2722-2726, Canadian Science Publishing [doi].

  147. Burton, RM; Obel, B, "Preface", TechnovationJanuary,, 1986, 5(1-3), 7 [doi].

  148. BUNCE, NJ; TOONE, EJ, "PHOTOCHEMISTRY OF BENZOPHENONE IN ACIDIFIED METHANOL", JOURNAL OF CHEMICAL RESEARCH-SJanuary,, 1983, 5(5), 115-115, ROYAL SOC CHEMISTRY [Gateway.cgi].

  149. Bunce, NJ; Deschutter, CT; Toone, EJ, "Photolysis of some ortho-methylated monochlorobiphenyls", Journal of the Chemical Society, Perkin Transactions 2January,, 1983, 6(6), 859-861, Royal Society of Chemistry (RSC) [doi] [abs].

Chapter in Book

  1. Broder, J, "Preface", in Diagnostic Imaging for the Emergency Physician, 2011, 78 1, xi-xii, Elsevier [doi].

  2. Burkhalter, NF; Dimick, SM; Toone, EJ, "Protein-carbohydrate interaction: Fundamental considerations", in Carbohydrates in Chemistry and BiologyApril,, 2008, 2-4, 863-914 [doi].

  3. Burkhalter, N.F.; Dimick, S.M.; Toone, E.J., "Protein-Carbohydrate Interaction. Fundamental Considerations", in Oligosaccharides in Chemistry and Biology: A Comprehensive Handbook, edited by Ernst, B. , 2000, VCH-Wiley.

  4. Henderson, D.F.; Toone, E.J., "Aldolases", in Comprehensive Natural Product Chemistry, Vol. 3 (Carbohydrates and Their Derivatives Including Tannins, Cellulose and Related Lignins), edited by Pinto, B.M. , 1999, 367-441, Elsevier: New York.

  5. Dodds, DR; Toone, PEJ, "Preface"January,, 1994, 2, xiii [doi].

Other

  1. Toone, E.J.; Stamler, J.S., "Stable Derivatives of NO for Controlled Delivery of NO in Biomedical Applications", US/Int Patent Application, 2004.