Publications of Katherine J. Franz

Journal Articles

  1. Reznik, N; Gallo, AD; Rush, KW; Javitt, G; Fridmann-Sirkis, Y; Ilani, T; Nairner, NA; Fishilevich, S; Gokhman, D; Chacón, KN; Franz, KJ; Fass, D, "Intestinal mucin is a chaperone of multivalent copper.", CellOctober,, 2022, 185(22), 4206-4215.e11 [doi] [abs].

  2. Campbell, JX; Gao, S; Anand, KS; Franz, KJ, "Zinc Binding Inhibits Cellular Uptake and Antifungal Activity of Histatin-5 in Candida albicans.", Acs Infectious DiseasesSeptember,, 2022, 8(9), 1920-1934 [doi] [abs].

  3. Hašková, P; Applová, L; Jansová, H; Homola, P; Franz, KJ; Vávrová, K; Roh, J; Šimůnek, T, "Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine.", Scientific ReportsJune,, 2022, 12(1), 9765 [doi] [abs].

  4. Zhang, T; Kephart, J; Bronson, E; Anand, M; Daly, C; Spasojevic, I; Bakthavatsalam, S; Franz, K; Berg, H; Karachaliou, GS; James, OG; Howard, L; Halabi, S; Harrison, MR; Armstrong, AJ; George, DJ, "Prospective clinical trial of disulfiram plus copper in men with metastatic castration-resistant prostate cancer.", ProstateMay,, 2022, 82(7), 858-866 [doi] [abs].

  5. Ge, EJ; Bush, AI; Casini, A; Cobine, PA; Cross, JR; DeNicola, GM; Dou, QP; Franz, KJ; Gohil, VM; Gupta, S; Kaler, SG; Lutsenko, S; Mittal, V; Petris, MJ; Polishchuk, R; Ralle, M; Schilsky, ML; Tonks, NK; Vahdat, LT; Van Aelst, L; Xi, D; Yuan, P; Brady, DC; Chang, CJ, "Connecting copper and cancer: from transition metal signalling to metalloplasia.", Nature Reviews. CancerFebruary,, 2022, 22(2), 102-113 [doi] [abs].

  6. Salcedo-Sora, JE; Robison, ATR; Zaengle-Barone, J; Franz, KJ; Kell, DB, "Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in Escherichia coli.", Molecules (Basel, Switzerland)September,, 2021, 26(19), 5826 [doi] [abs].

  7. Hunsaker, EW; Yu, C-HA; Franz, KJ, "Copper Availability Influences the Transcriptomic Response of Candida albicans to Fluconazole Stress.", G3 (Bethesda, Md.)April,, 2021, 11(4), jkab065 [doi] [abs].

  8. Jackson, AC; Pinter, TBJ; Talley, DC; Baker-Agha, A; Patel, D; Smith, PJ; Franz, KJ, "Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo-β-Lactamase NDM-1.", ChemmedchemFebruary,, 2021, 16(4), 654-661 [doi] [abs].

  9. Razgoniaev, AO; Glasstetter, LM; Kouznetsova, TB; Hall, KC; Horst, M; Craig, SL; Franz, KJ, "Single-Molecule Activation and Quantification of Mechanically Triggered Palladium-Carbene Bond Dissociation.", Journal of the American Chemical SocietyFebruary,, 2021, 143(4), 1784-1789 [doi] [abs].

  10. Wiebelhaus, N; Zaengle-Barone, JM; Hwang, KK; Franz, KJ; Fitzgerald, MC, "Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli.", Acs Chemical BiologyJanuary,, 2021, 16(1), 214-224 [doi] [abs].

  11. Hunsaker, EW; McAuliffe, KJ; Franz, KJ, "Fluconazole analogues with metal-binding motifs impact metal-dependent processes and demonstrate antifungal activity in Candida albicans.", Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic ChemistryAugust,, 2020, 25(5), 729-745 [doi] [abs].

  12. Bakthavatsalam, S; Wiangnak, P; George, DJ; Zhang, T; Franz, KJ, "Dithiocarbamate prodrugs activated by prostate specific antigen to target prostate cancer.", Bioorg Med Chem LettJune,, 2020, 30(11), 127148 [doi] [abs].

  13. Jackson, AC; Zaengle-Barone, JM; Puccio, EA; Franz, KJ, "A Cephalosporin Prochelator Inhibits New Delhi Metallo-β-lactamase 1 without Removing Zinc.", Acs Infectious DiseasesMay,, 2020, 6(5), 1264-1272 [doi] [abs].

  14. Zaengle-Barone, JM; Jackson, AC; Besse, DM; Becken, B; Arshad, M; Seed, PC; Franz, KJ, "Correction to Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria.", Acs Infectious DiseasesApril,, 2020, 6(4), 759 [doi].

  15. Gallo, AD; Franz, KJ, "Grab 'n Go: Siderophore-Binding Proteins Provide Pathogens a Quick Fix to Satisfy Their Hunger for Iron.", Acs Central ScienceApril,, 2020, 6(4), 456-458 [doi].

  16. Garcia-Santamarina, S; Probst, C; Festa, RA; Ding, C; Smith, AD; Conklin, SE; Brander, S; Kinch, LN; Grishin, NV; Franz, KJ; Riggs-Gelasco, P; Lo Leggio, L; Johansen, KS; Thiele, DJ, "A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis.", Nature Chemical BiologyMarch,, 2020, 16(3), 337-344 [doi] [abs].

  17. Hunsaker, EW; Franz, KJ, "Candida albicans reprioritizes metal handling during fluconazole stress.", Metallomics : Integrated Biometal ScienceDecember,, 2019, 11(12), 2020-2032 [doi] [abs].

  18. Hunsaker, EW; Franz, KJ, "Emerging Opportunities To Manipulate Metal Trafficking for Therapeutic Benefit.", Inorganic ChemistryOctober,, 2019, 58(20), 13528-13545 [doi] [abs].

  19. Hunsaker, EW; Franz, KJ, "Copper potentiates azole antifungal activity in a way that does not involve complex formation.", Dalton Transactions (Cambridge, England : 2003)July,, 2019, 48(26), 9654-9662 [doi] [abs].

  20. Franz, KJ; Metzler-Nolte, N, "Introduction: Metals in Medicine.", Chemical ReviewsJanuary,, 2019, 119(2), 727-729 [doi].

  21. Franz, KJ, "Metallomics: Emerging Investigators 2019.", Metallomics : Integrated Biometal ScienceJanuary,, 2019, 11(1), 9-14 [doi].

  22. Wang, Q; Franz, KJ, "Modifying aroylhydrazone prochelators for hydrolytic stability and improved cytoprotection against oxidative stress.", Bioorganic & Medicinal ChemistryDecember,, 2018, 26(22), 5962-5972 [doi] [abs].

  23. Bakthavatsalam, S; Sleeper, ML; Dharani, A; George, DJ; Zhang, T; Franz, KJ, "Leveraging γ-Glutamyl Transferase To Direct Cytotoxicity of Copper Dithiocarbamates against Prostate Cancer Cells.", Angew Chem Int Ed EnglSeptember,, 2018, 57(39), 12780-12784 [doi] [abs].

  24. Zaengle-Barone, JM; Jackson, AC; Besse, DM; Becken, B; Arshad, M; Seed, PC; Franz, KJ, "Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria.", Acs Infectious DiseasesJune,, 2018, 4(6), 1019-1029 [doi] [abs].

  25. Hall, KC; Franks, AT; McAtee, RC; Wang, MS; Lu, VI; Franz, KJ, "Metal-binding hydrazone photoswitches for visible light reactivity and variable relaxation kinetics.", Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for PhotobiologyNovember,, 2017, 16(11), 1604-1612 [doi] [abs].

  26. Wang, Q; Franz, KJ, "The hydrolytic susceptibility of prochelator BSIH in aqueous solutions.", Bioorganic & Medicinal Chemistry LettersSeptember,, 2017, 27(17), 4165-4170 [doi] [abs].

  27. Conklin, SE; Bridgman, EC; Su, Q; Riggs-Gelasco, P; Franz, KJ, "Specific Histidine Residues Confer Histatin Peptides with Copper-Dependent Activity against Candida albicans", BiochemistryAugust,, 2017, 56(32), 4244-4255, American Chemical Society [doi] [abs].

  28. Franz, KJ, "Chemical Approaches for Manipulating Microbial Metals", Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic ChemistryJuly,, 2017, 22, S215-S215, SPRINGER.

  29. Helsel, ME; White, EJ; Razvi, SZA; Alies, B; Franz, KJ, "Chemical and functional properties of metal chelators that mobilize copper to elicit fungal killing of Cryptococcus neoformans.", Metallomics : Integrated Biometal ScienceJanuary,, 2017, 9(1), 69-81 [doi] [abs].

  30. Sansee, A; Meksawangwong, S; Chainok, K; Franz, KJ; Gál, M; Pålsson, L-O; Puniyan, W; Traiphol, R; Pal, R; Kielar, F, "Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains.", Dalton Transactions (Cambridge, England : 2003)November,, 2016, 45(43), 17420-17430 [doi] [abs].

  31. Wang, Q; Franz, KJ, "Stimulus-Responsive Prochelators for Manipulating Cellular Metals.", Accounts of Chemical ResearchNovember,, 2016, 49(11), 2468-2477 [doi] [abs].

  32. Hašková, P; Jansová, H; Bureš, J; Macháček, M; Jirkovská, A; Franz, KJ; Kovaříková, P; Šimůnek, T, "Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury.", ToxicologySeptember,, 2016, 371, 17-28 [doi] [abs].

  33. Jansová, H; Bureš, J; Macháček, M; Hašková, P; Jirkovská, A; Roh, J; Wang, Q; Franz, KJ; Kovaříková, P; Šimůnek, T, "Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products.", ToxicologyMarch,, 2016, 350-352, 15-24 [doi] [abs].

  34. Franks, AT; Wang, Q; Franz, KJ, "A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress.", Bioorganic & Medicinal Chemistry LettersNovember,, 2015, 25(21), 4843-4847 [doi] [abs].

  35. Pushie, MJ; Shaw, K; Franz, KJ; Shearer, J; Haas, KL, "Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1.", Inorganic ChemistrySeptember,, 2015, 54(17), 8544-8551 [doi] [abs].

  36. Alies, B; Wiener, JD; Franz, KJ, "A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity.", Chem. Sci.June,, 2015, 6(6), 3606-3610 [doi] [abs].

  37. Crumbliss, AL; Franz, KJ; Thiele, DJ, "Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA.", Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and MedicineJune,, 2015, 28(3), 431 [doi].

  38. Helsel, ME; Franz, KJ, "Pharmacological activity of metal binding agents that alter copper bioavailability.", Dalton Transactions (Cambridge, England : 2003)May,, 2015, 44(19), 8760-8770 [doi] [abs].

  39. Bureš, J; Jansová, H; Stariat, J; Filipský, T; Mladěnka, P; Šimůnek, T; Kučera, R; Klimeš, J; Wang, Q; Franz, KJ; Kovaříková, P, "LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH).", Journal of Pharmaceutical and Biomedical AnalysisFebruary,, 2015, 105, 55-63 [doi] [abs].

  40. Safi, R; Nelson, ER; Chitneni, SK; Franz, KJ; George, DJ; Zalutsky, MR; McDonnell, DP, "Copper signaling axis as a target for prostate cancer therapeutics.", Cancer ResOctober,, 2014, 74(20), 5819-5831 [repository], [doi] [abs].

  41. Franks, AT; Franz, KJ, "A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting.", Chemical CommunicationsOctober,, 2014, 50(77), 11317-11320 [doi] [abs].

  42. Jansová, H; Macháček, M; Wang, Q; Hašková, P; Jirkovská, A; Potůčková, E; Kielar, F; Franz, KJ; Simůnek, T, "Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury.", Free Radical Biology and MedicineSeptember,, 2014, 74, 210-221 [doi] [abs].

  43. Festa, RA; Helsel, ME; Franz, KJ; Thiele, DJ, "Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection.", Chemistry & BiologyAugust,, 2014, 21(8), 977-987 [doi] [abs].

  44. Festa, RA; Helsel, ME; Franz, KJ; Thiele, DJ, "Innate immune cell activation of a copper-dependent anti-cryptococcal agent", MycosesMay,, 2014, 57, 56-57, WILEY-BLACKWELL.

  45. Franz, KJ, "Manipulating metals at the host-pathogen interface", Abstracts of Papers of the American Chemical SocietyMarch,, 2014, 247, 1 pages, AMER CHEMICAL SOC.

  46. Franks, AT; Peng, D; Yang, W; Franz, KJ, "Characterization of a photoswitching chelator with light-modulated geometric, electronic, and metal-binding properties.", Inorganic ChemistryFebruary,, 2014, 53(3), 1397-1405 [doi] [abs].

  47. Grant, GA; Hankinson, T; Muh, C; Dumont, A, "The 62nd Annual Meeting of the Congress of Neurological Surgeons was held in Chicago, Illinois from October 6-10, 2012. Preface.", NeurosurgeryAugust,, 2013, 60 Suppl 1, v [doi].

  48. Franks, A; Helsel, M; Franz, KJ, "Development of stimulus-responsive metal chelation with novel fluorescence reporting", Abstracts of Papers of the American Chemical SocietyApril,, 2013, 245, 1 pages, AMER CHEMICAL SOC.

  49. Franz, KJ, "Clawing back: broadening the notion of metal chelators in medicine.", Current Opinion in Chemical BiologyApril,, 2013, 17(2), 143-149 [23332666], [doi] [abs].

  50. Kumbhar, AA; Franks, AT; Butcher, RJ; Franz, KJ, "Light uncages a copper complex to induce nonapoptotic cell death.", Chemical CommunicationsMarch,, 2013, 49(24), 2460-2462, The Royal Society of Chemistry [23417227], [doi] [abs].

  51. Folk, DS; Kielar, F; Franz, KJ, "Bioinorganic Neurochemistry"January,, 2013, 3, 207-240, Elsevier [doi] [abs].

  52. Kielar, F; Wang, Q; Boyle, PD; Franz, KJ, "A boronate prochelator built on a triazole framework for peroxide-triggered tridentate metal binding.", Inorganica Chimica ActaDecember,, 2012, 3930, 294-303 [23439614], [doi] [abs].

  53. Folk, DS; Torosian, JC; Hwang, S; McCafferty, DG; Franz, KJ, "Monitoring β-secretase activity in living cells with a membrane-anchored FRET probe.", Angewandte Chemie International EditionOctober,, 2012, 51(43), 10795-10799 [23023944], [doi].

  54. Hyman, LM; Franz, KJ, "Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols.", Coordination Chemistry ReviewsOctober,, 2012, 256(19-20), 2333-2356 (Special Issue on Metal Ions in Neurodegenerative Diseases http://dx.doi.org/10.1016/j.ccr.2012.03.009.) [23440254], [doi] [abs].

  55. Kielar, F; Helsel, ME; Wang, Q; Franz, KJ, "Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation.", Metallomics : Integrated Biometal ScienceAugust,, 2012, 4(9), 899-909 [22700084], [doi] [abs].

  56. Franz, KJ, "Application of inorganic chemistry for non-cancer therapeutics.", Dalton Transactions (Cambridge, England : 2003)June,, 2012, 41(21), 6333-6334 ((guest editorial for themed issue).) [C2DT90061K], [doi].

  57. Franz, KJ, "Optimizing prochelators to bind metal ions in response to disease-associated stimuli[p]", Abstracts of Papers of the American Chemical SocietyMarch,, 2012, 243, 1 pages, AMER CHEMICAL SOC.

  58. Folk, DS; Torosian, J; Franz, KJ, "BACE activated prochelator mediates A beta-Cu toxicity in an Alzheimer's disease cell model", Abstracts of Papers of the American Chemical SocietyMarch,, 2012, 243, 1 pages, AMER CHEMICAL SOC.

  59. Rubino, JT; Franz, KJ, "Coordination chemistry of copper proteins: how nature handles a toxic cargo for essential function.", Journal of Inorganic BiochemistryFebruary,, 2012, 107(1), 129-143 (invited contribution for an “Early Career Focused Review”.) [22204943], [doi] [abs].

  60. Hyman, LM; Franz, KJ, "A Cell-Permeable Fluorescent Prochelator Responds to Hydrogen Peroxide and Metal Ions by Decreasing Fluorescence.", Inorganica Chimica ActaJanuary,, 2012, 380, 125-134 (invited contribution for special issue: "Inorganic Chemistry - The Next Generation").) [22287796], [doi] [abs].

  61. Zielonka, J; Kielar, F; Sikora, A; Franz, KJ; Kalyanaraman, B, "Dual Antioxidant Activity of Boronate-Based Prochelators: Scavenging Peroxynitrite and Metal Ion Chelation", Free Radical Biology and MedicineNovember,, 2011, 51, S100-S101, Elsevier BV [doi].

  62. Leed, MGD; Wolkow, N; Pham, DM; Daniel, CL; Dunaief, JL; Franz, KJ, "Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress.", Journal of Inorganic BiochemistrySeptember,, 2011, 105(9), 1161-1172 (http://dx.doi.org/10.1016/j.jinorgbio.2011.05.023.) [21708101], [doi] [abs].

  63. Franz, KJ, "Design of prochelators that bind cellular metal ions in response to diverse stimuli", Abstracts of Papers of the American Chemical SocietyAugust,, 2011, 242, 1 pages, AMER CHEMICAL SOC.

  64. Haas, KL; Putterman, AB; White, DR; Thiele, DJ; Franz, KJ, "Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1.", Journal of the American Chemical SocietyMarch,, 2011, 133(12), 4427-4437 (doi: 10.1021/ja108890c.) [21375246], [doi] [abs].

  65. Rubino, JT; Chenkin, MP; Keller, M; Riggs-Gelasco, P; Franz, KJ, "A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments.", Metallomics : Integrated Biometal ScienceJanuary,, 2011, 3(1), 61-73 [21553704], [doi] [abs].

  66. Ciesienski, KL; Franz, KJ, "Keys for unlocking photolabile metal-containing cages.", Angewandte Chemie International EditionJanuary,, 2011, 50(4), 814-824 [21246677], [doi] [abs].

  67. Ciesienski, KL; Haas, KL; Franz, KJ, "Development of next-generation photolabile copper cages with improved copper binding properties.", Dalton Transactions (Cambridge, England : 2003)October,, 2010, 39(40), 9538-9546 [20740238], [doi] [abs].

  68. Rubino, JT; Riggs-Gelasco, P; Franz, KJ, "Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I).", Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic ChemistrySeptember,, 2010, 15(7), 1033-1049 [20437064], [doi] [abs].

  69. Franz, KJ; Haas, KL, "Insights into the role of histidine in Ctr1-dependent copper uptake", Abstracts of Papers of the American Chemical SocietyAugust,, 2010, 240, 1 pages, AMER CHEMICAL SOC.

  70. Hyman, LM; Franz, KJ, "Development of triggereable chelating agents as probes for metal-induced oxidative stress", Abstracts of Papers of the American Chemical SocietyAugust,, 2010, 240, 1 pages, AMER CHEMICAL SOC.

  71. Ciesienski, KL; Hyman, LM; Derisavifard, S; Franz, KJ, "Toward the detection of cellular copper(II) by a light-activated fluorescence increase.", Inorganic ChemistryAugust,, 2010, 49(15), 6808-6810 [20590142], [doi].

  72. Ciesienski, KL; Hyman, LM; Yang, DT; Haas, KL; Dickens, MG; Holbrook, RJ; Franz, KJ, "A photo-caged platinum(II) complex that increases cytotoxicity upon light activation", European Journal of Inorganic ChemistryMay,, 2010, 2010(15), 2224-2228, WILEY [doi] [abs].

  73. Folk, DS; Franz, KJ, "A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation.", Journal of the American Chemical SocietyApril,, 2010, 132(14), 4994-4995 [20297791], [doi] [abs].

  74. Franz, KJ; He, C, "The highways and byways of bioinorganic chemistry.", Current Opinion in Chemical BiologyApril,, 2010, 14(2), 208-210 [doi].

  75. Franz, KJ, "Recent developments in the design of triggerable chelating agents for altering metal coordination in biological settings", Abstracts of Papers of the American Chemical SocietyMarch,, 2010, 239, 1 pages, AMER CHEMICAL SOC.

  76. Tangen, E; Conradie, J; Franz, K; Friedle, S; Telser, J; Lippard, SJ; Ghosh, A, "Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand.", Inorganic ChemistryMarch,, 2010, 49(6), 2701-2705 [doi] [abs].

  77. Perez, LR; Franz, KJ, "Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease.", Dalton Transactions (Cambridge, England : 2003)March,, 2010, 39(9), 2177-2187 [20162187], [doi] [abs].

  78. Crider, SE; Holbrook, RJ; Franz, KJ, "Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1.", Metallomics : Integrated Biometal ScienceJanuary,, 2010, 2(1), 74-83 (doi:10.1039/b916899k.) [21072377], [doi] [abs].

  79. Dickens, MG; Franz, KJ, "A prochelator activated by hydrogen peroxide prevents metal-induced amyloid Beta aggregation.", Chembiochem : a European Journal of Chemical BiologyJanuary,, 2010, 11(1), 59-62 [19937900], [doi].

  80. Hyman, LM; Stephenson, CJ; Dickens, MG; Shimizu, KD; Franz, KJ, "Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress.", Dalton Transactions (Cambridge, England : 2003)January,, 2010, 10.1039/b914568k(2), 568-576 [20023995], [doi] [abs].

  81. Palmer, AE; Franz, KJ, "Introduction to "cellular metal homeostasis and trafficking".", Chemical ReviewsOctober,, 2009, 109(10), 4533-4535 [doi].

  82. Haas, KL; Franz, KJ, "Application of metal coordination chemistry to explore and manipulate cell biology.", Chemical ReviewsOctober,, 2009, 109(10), 4921-4960 [19715312], [doi].

  83. Rubino, JT; Franz, KJ, "Characterization of thioether-only Cu(I) binding by Ctr1 methionine motifs", Abstracts of Papers of the American Chemical SocietyAugust,, 2009, 238, 1 pages, AMER CHEMICAL SOC.

  84. Dickens, MG; Daniel, CL; Pham, DM; Franz, KJ, "Synthesis of masked bidentate and hexadentate iron chelators designed to reduce oxidative stress", Abstracts of Papers of the American Chemical SocietyAugust,, 2009, 238, 1 pages, AMER CHEMICAL SOC.

  85. Haas, KL; White, DR; Franz, KJ, "Spectroscopic studies of N-terminal Cu(II)- and Cu(I)-binding hCtrl model peptides", Abstracts of Papers of the American Chemical SocietyAugust,, 2009, 238, 1 pages, AMER CHEMICAL SOC.

  86. Franz, KJ, "Design of triggerable ligands for altering metal coordination in biological settings", Abstracts of Papers of the American Chemical SocietyAugust,, 2009, 238, 1 pages, AMER CHEMICAL SOC.

  87. Ciesienski, KL; Haas, KL; Dickens, MG; Franz, KJ, "Photolabile ligand for light-activated release of caged copper", Abstracts of Papers of the American Chemical SocietyMarch,, 2009, 237, 1 pages, AMER CHEMICAL SOC.

  88. Charkoudian, LK; Dentchev, T; Lukinova, N; Wolkow, N; Dunaief, JL; Franz, KJ, "Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide.", Journal of Inorganic BiochemistryDecember,, 2008, 102(12), 2130-2135 (Young Investigator Special Issue on “Inorganic Biochemistry - The Next Generation”.) [18835041], [doi] [abs].

  89. Ciesienski, KL; Haas, KL; Dickens, MG; Tesema, YT; Franz, KJ, "A photolabile ligand for light-activated release of caged copper.", Journal of the American Chemical SocietySeptember,, 2008, 130(37), 12246-12247 [18714999], [doi] [abs].

  90. Hunt, LM; Franz, KJ, "INOR 273-Development of prochelators as probes of iron-induced oxidative stress", Abstracts of Papers of the American Chemical SocietyApril,, 2008, 235, 1 pages, AMER CHEMICAL SOC.

  91. Crider, SE; Franz, KJ, "INOR 277-Interactions of cisplatin and methionine-rich peptide domains of the human high-affinity copper transporter Ctr1", Abstracts of Papers of the American Chemical SocietyApril,, 2008, 235, 1 pages, AMER CHEMICAL SOC.

  92. Tesema, YT; Pham, DM; Franz, KJ, "Counterions influence reactivity of metal ions with cysteinyldopa model compounds.", Inorganic ChemistryFebruary,, 2008, 47(3), 1087-1095 [18163613], [doi] [abs].

  93. Franz, KJ, "Copper shares a piece of the pi.", Nature Chemical BiologyFebruary,, 2008, 4(2), 85-86 [nchembio0208-85], [doi] [abs].

  94. Charkoudian, LK; Pham, DM; Kwon, AM; Vangeloff, AD; Franz, KJ, "Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress.", Dalton Transactions (Cambridge, England : 2003)November,, 2007, 43(43), 5031-5042 [17992288], [doi] [abs].

  95. Franz, KJ; Charkoudian, LK, "INOR 916-A pro-chelator strategy for inhibiting metal-catalyzed oxidative stress", Abstracts of Papers of the American Chemical SocietyAugust,, 2007, 234, 1 pages, AMER CHEMICAL SOC.

  96. Liu, LL; Franz, KJ, "Phosphorylation-dependent metal binding by alpha-synuclein peptide fragments.", Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic ChemistryFebruary,, 2007, 12(2), 234-247 [17082919], [doi] [abs].

  97. Charkoudian, LK; Franz, KJ, "INOR 614-Development of iron chelators triggered by reactive oxygen species", Abstracts of Papers of the American Chemical SocietySeptember,, 2006, 232, 1 pages, AMER CHEMICAL SOC.

  98. Franz, KJ; Haas, K; Rubino, J; Pham, D, "INOR 1011-Copper(I) binding by methionine-rich domains of copper transport proteins", Abstracts of Papers of the American Chemical SocietySeptember,, 2006, 232, 1 pages, AMER CHEMICAL SOC.

  99. Charkoudian, LK; Pham, DM; Franz, KJ, "A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation.", Journal of the American Chemical SocietySeptember,, 2006, 128(38), 12424-12425 [16984186], [doi] [abs].

  100. Tesema, YT; Pham, DM; Franz, KJ, "Synthesis and characterization of copper(II) complexes of cysteinyldopa and benzothiazine model ligands related to pheomelanin.", Inorganic ChemistryAugust,, 2006, 45(16), 6102-6104 [16878910], [doi] [abs].

  101. Charkoudian, LK; Franz, KJ, "Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid.", Inorganic ChemistryMay,, 2006, 45(9), 3657-3664 [16634598], [doi] [abs].

  102. Jiang, J; Nadas, IA; Kim, MA; Franz, KJ, "A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination.", Inorganic ChemistryDecember,, 2005, 44(26), 9787-9794 [16363848], [doi] [abs].

  103. Liu, LL; Franz, KJ, "Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding.", Journal of the American Chemical SocietyJuly,, 2005, 127(27), 9662-9663 [15998051], [doi] [abs].

  104. Liu, LL; Franz, KJ, "Characterization of metal binding sites in a synthetic phosphorylated alpha-synuclein peptide fragment.", Abstracts of Papers of the American Chemical SocietyMarch,, 2005, 229, U1080-U1081, AMER CHEMICAL SOC.

  105. Nitz, M; Sherawat, M; Franz, KJ; Peisach, E; Allen, KN; Imperiali, B, "Structural origin of the high affinity of a chemically evolved lanthanide-binding peptide.", Angewandte Chemie International EditionJuly,, 2004, 43(28), 3682-3685 [doi] [abs].

  106. Wöhnert, J; Franz, KJ; Nitz, M; Imperiali, B; Schwalbe, H, "Protein alignment by a coexpressed lanthanide-binding tag for the measurement of residual dipolar couplings.", Journal of the American Chemical SocietyNovember,, 2003, 125(44), 13338-13339 [doi] [abs].

  107. Franz, KJ; Nitz, M; Lukovic, E; Imperiali, B, "Development of lanthanide-binding peptides as natively expressed protein probes", Journal of Inorganic BiochemistryJuly,, 2003, 96(1), 131-131, Elsevier BV [doi].

  108. Nitz, M; Franz, KJ; Maglathlin, RL; Imperiali, B, "A powerful combinatorial screen to identify high-affinity terbium(III)-binding peptides.", Chembiochem : a European Journal of Chemical BiologyApril,, 2003, 4(4), 272-276 [doi] [abs].

  109. Franz, KJ; Nitz, M; Imperiali, B, "Lanthanide-binding tags as versatile protein coexpression probes.", Chembiochem : a European Journal of Chemical BiologyApril,, 2003, 4(4), 265-271 [doi] [abs].

  110. Franz, KJ; Doerrer, LH; Spingler, B; Lippard, SJ, "Pentacoordinate cobalt(III) thiolate and nitrosyl tropocoronand compounds.", Inorganic ChemistryJuly,, 2001, 40(15), 3774-3780, AMER CHEMICAL SOC [doi] [abs].

  111. Franz, KJ; Singh, N; Spingler, B; Lippard, SJ, "Aminotroponiminates as ligands for potential metal-based nitric oxide sensors.", Inorganic ChemistrySeptember,, 2000, 39(18), 4081-4092 [doi] [abs].

  112. Franz, KJ; Lippard, SJ, "Nitrosyl transfer from manganese to iron in tropocoronand complexes.", Inorganic ChemistryAugust,, 2000, 39(16), 3722-3723 [doi] [abs].

  113. Franz, KJ; Singh, N; Lippard, SJ, "Metal-based NO sensing by selective ligand dissociation", Angewandte Chemie International Edition, 2000, 39(12), 2120-2122, WILEY [doi] [abs].

  114. Franz, KJ; Lippard, SJ, "NO disproportionation reactivity of Fe tropocoronand complexes", Journal of the American Chemical SocietyNovember,, 1999, 121(45), 10504-10512, American Chemical Society (ACS) [doi] [abs].

  115. Franz, KJ; Lippard, SJ; Marlin, D; Mascharak, P, "Disproportionation of nitric oxide promoted by a Mn tropocoronand", ChemtractsFebruary,, 1999, 12(2), 135-140.

  116. Loehlin, JH; Franz, KJ; Gist, L; Moore, RH, "Supramolecular Alcohol-Amine Crystals and Their Hydrogen-Bond Patterns", Acta Crystallographica Section B Structural ScienceOctober,, 1998, 54(5), 695-704, International Union of Crystallography (IUCr) [doi] [abs].

  117. Franz, KJ; Lippard, SJ, "Disproportionation of nitric oxide promoted by a Mn tropocoronand", Journal of the American Chemical SocietySeptember,, 1998, 120(35), 9034-9040, American Chemical Society (ACS) [doi] [abs].

  118. Huang, SP; Franz, KJ; Arnold, EH; Devenyi, J; Fish, RH, "Polymer pendant ligand chemistry-5. The selective and competitive removal of Ag+, Hg2+, Cu2+, Pb2+ and Cd2+ ions from aqueous solution utilizing a N-sulfonylethylenebis(dithiocarbamate) ligand anchored on macroporous polystyrene-divinylbenzene beads", PolyhedronSeptember,, 1996, 15(23), 4241-4254, Elsevier BV [doi] [abs].

  119. Huang, SP; Franz, KJ; Olmstead, MM; Fish, RH, "Synthetic and Structural Studies of a Linear Bis-Catechol Amide, N,N′-Bis(2,3-dihydroxybenzoyl)-1,7-diazaheptane (5-LICAM), and Its Complexes with Ni2+ and Co2+: Utilization of a Polymer-Supported, Sulfonated Analog, 5-LICAMS, as a Biomimetic Ligand for Divalent Metal Ion Removal from Aqueous Solution", Inorganic ChemistryMay,, 1995, 34(11), 2820-2825, American Chemical Society (ACS) [doi] [abs].

  120. Huang, SP; Li, W; Franz, KJ; Albright, RL; Fish, RH, "Polymer Pendant Ligand Chemistry. 3. A Biomimetic Approach to Selective Metal Ion Removal and Recovery from Aqueous Solution with Polymer-Supported Sulfonated Catechol and Linear Catechol Amide Ligands", Inorganic ChemistryMay,, 1995, 34(11), 2813-2819, American Chemical Society (ACS) [doi] [abs].

Chapter in Book

  1. Wang, Q; Franz, KJ, "Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes", in Inorganic Chemical Biology: Principles, Techniques and ApplicationsJune,, 2014, 9781118510025, 233-274, JOHN WILEY & SONS LTD [doi] [abs].

  2. Franz, K. J.; Wang, Q., "Detection of Metal Ions, Anions, Small Molecules and Biomolecules using Metal Complexes", in Inorganic Chemical Biology: Principles, Techniques and Applications, edited by Gasser, G., Ed. , 2014, John Wiley & Sons, Ltd: UK.