Publications [#371517] of Amanda Randles

Papers Published

1. Tanade, C; Putney, S; Randles, A, Establishing massively parallel models to examine the influence of cell heterogeneity on tumor growth, Journal of Computational Science, vol. 71 (July, 2023) [doi]
   (last updated on 2025/12/31)

   Abstract:
   Parallel 3D cellular automaton models of tumor growth can efficiently capture emergent morphology. We extended a 2D growth model to 3D to examine the influence of symmetric division in heterogeneous tumors on growth dynamics. As extending to 3D severely increased time-to-solution, we parallelized the model using N-body, lattice halo exchange, and adaptive communication schemes. Supplementing prior work from Tanade et al. (2022), we demonstrated over 55x speedup and evaluated performance on ≤30 nodes of Stampede2. This work established a framework to parametrically study 3D growth dynamics, and of the cancer phenotypes we studied, the parallel model better scaled when tumor boundaries were radially symmetric.