Publications [#252081] of Ahmad Hariri

Journal Articles

1. Fisher, PM; Meltzer, CC; Ziolko, SK; Price, JC; Moses-Kolko, EL; Berga, SL; Hariri, AR (2006). Capacity for 5-HT1A-mediated autoregulation predicts amygdala reactivity.. Nature neuroscience, 9(11), 1362-1363. [doi]
   (last updated on 2024/04/25)

   Abstract:
   We examined the contribution of 5-HT1A autoreceptors (with [11C]WAY100635 positron emission tomography) to amygdala reactivity (with blood oxygenation level-dependent functional magnetic resonance imaging) in 20 healthy adult volunteers. We found a significant inverse relationship wherein 5-HT1A autoreceptor density predicted a notable 30-44% of the variability in amygdala reactivity. Our data suggest a potential molecular mechanism by which a reduced capacity for negative feedback regulation of 5-HT release is associated with increased amygdala reactivity.