Publications [#185950] of Herbert E Covington, III

Journal Articles

1. Yap, Jasmine J. and Covington, Herbert E. and Gale, Melissa C. and Datta, Rupak and Miczek, Klaus A. (2005). Behavioral sensitization due to social defeat stress in mice: antagonism at mGluR5 and NMDA receptors.. Psychopharmacology, 179(1), 230--239. [15517195], [doi]
   (last updated on 2011/01/03)

   Abstract:
   Repeated administration of psychostimulants progressively augments the behavioral response to and increases self-administration behavior of these drugs. Experience of repeated intermittent social defeat stress episodes also leads to a sensitized locomotor response following psychostimulant challenge. Both metabotropic and ionotropic glutamate receptors have been shown to be critical in the induction and expression of stimulant sensitization, but their role in sensitization due to social defeat stress remains unclear.