| Publications [#185959] of Herbert E Covington, III
search PubMed.Journal Articles
- Fowler, Stephen C. and Covington, Herbert E. and Miczek, Klaus A. (2007). Stereotyped and complex motor routines expressed during cocaine self-administration: results from a 24-h binge of unlimited cocaine access in rats.. Psychopharmacology, 192(4), 465--478. [17333134], [doi]
(last updated on 2011/12/30)
Abstract: Cocaine binges represent the most severe form of cocaine taking due to high levels of cocaine consumed and a potential loss of self-control over cocaine taking. Experimentally, regulation of intravenous cocaine self-administration is observed during binges as revealed by nearly constant sequential inter-infusion intervals, suggesting that pharmacological and unconditioned behavioral effects of cumulative cocaine leave intact its reinforcing effect.
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