Publications [#99829] of Bruce A Sullenger

Papers Published

1. BA Sullenger, Revising messages traveling along the cellular information superhighway., Chemistry & biology, vol. 2 no. 5 (May, 1995), pp. 249-53, ISSN 1074-5521
   (last updated on 2013/05/16)

   Abstract:
   Cells use RNA messages to carry instructions from the genome to ribosomes about the types of proteins that should be made. These messages are generally revised by splicing before translation. Engineering ribozymes that can use splicing to repair mutant transcripts may be a useful approach to gene therapy of several genetic diseases.

   Keywords:
   Animals • Cell Communication • Genetic Engineering • Genetic Therapy • Genome • Humans • Protein Biosynthesis* • RNA Splicing • RNA, Catalytic • RNA, Messenger • Ribosomes • Transcription, Genetic • genetics • metabolism • physiology • physiology*