Mohamed A. Noor, Professor
Education:
PhD, University of Chicago, 1996
BS, College of William and Mary, 1992
Office Location: FFSC: 4214
Office Phone: 919-613-8156
Email Address: noor@duke.edu
Web Page: http://www.biology.duke.edu/noorlab/Noorlab.html
Specialties:
Evolution
Genetics
Genomics
Research Categories: Speciation and evolutionary genetics, recombination
Research Description: One of the greatest unsolved questions in biology is how continuous processes of evolutionary change produce the discontinuous groups known as species. My research has focused on understanding the processes that cause the evolution of barriers to gene exchange between diverging species, particularly hybrid sterility and species mating discrimination. My approaches are primarily classical or molecular genetic using Drosophila species as model organisms. Using these approaches, we have dissected the genetic basis of these barriers to gene exchange using molecular markers and QTL mapping methodologies or gene expression approaches. The recent availability of multiple whole-genome sequences (both publicly and those we have obtained ourselves) has dramatically enhanced the scope of progress we can make. In addition to questions in speciation, we have recently been studying the effects of fine-scale recombination heterogeneity on various evolutionary parameters including nucleotide diversity, divergence, and codon bias. See my lab web page for more information.
Recent Publications (More Publications) (search)
- MAF Noor, Mutagenesis from meiotic recombination is not a primary driver of sequence divergence between Saccharomyces species., Molecular Biology and Evolution, vol. 25 no. 11 (November, 2008), pp. 2439-2444 [abs].
- MAF Noor, Connecting recombination, nucleotide diversity and species divergence in Drosophila., Fly, vol. 2 no. 5 (September, 2008) [abs].
- RJ Kulathinal, SM Bennett, CL Fitzpatrick, MAF Noor, Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence., Proceedings of the National Academy of Sciences USA, vol. 105 no. 29 (July, 2008), pp. 10051-6 [abs].
- DE Runcie, MAF Noor, Sequence signatures of a recent chromosomal rearrangement in Drosophila mojavensis., Genetica (July, Accepted, 2008) [abs].
- CV Barnwell, MAF Noor, Failure to replicate two mate preference QTLs across multiple strains of Drosophila pseudoobscura., Journal of Heredity, vol. 99 no. 6 (2008), pp. 653-656 [abs].
Duke Biology Box 90338 Durham, NC 27708 Phone: 919-660-7372 Fax: 919-660-7293