Mohamed A. Noor, Professor
PhD, University of Chicago, 1996
BS, College of William and Mary, 1992
Research Categories: Speciation and evolutionary genetics, recombination
Research Description: One of the greatest unsolved questions in biology is how continuous processes of evolutionary change produce the discontinuous groups known as species. For a many years, my team studied hybrid sterility and behavioral mate preferences using classical, QTL-based, or molecular genetic approaches on Drosophila species as model organisms. More recently, the availability of multiple whole-genome sequences (some public but especially those we have obtained ourselves) has dramatically enhanced the scope of progress we make. A major question we've sought to address has been determining the genetic features and evolutionary processes that allow hybridizing species to persist, with particular interest in recombination and chromosomal inversions. In addition to questions in speciation, we are broadly interested in molecular evolution within species, again with a particular focus on the effects of recombination. See my lab web page for more information.
- RB Myers, B Millman, MAF Noor, Genetics and evolution: an iOS application to supplement introductory courses in transmission and evolutionary genetics., G3, vol. 4 no. 5 (May, 2014), pp. 779-81 [doi] [abs].
- CSS Heil, B Manzano-Winkler, MJ Hunter, JKF Noor, MAF Noor, Witnessing evolution first-hand: A K-12 laboratory exercise in genetics and evolution using Drosophila, American Biology Teacher, vol. 75 (2013), pp. 116-119 , [doi] .
- B Manzano-Winkler, SE McGaugh, MAF Noor, How hot are drosophila hotspots? examining recombination rate variation and associations with nucleotide diversity, divergence, and maternal age in Drosophila pseudoobscura., PLoS One, vol. 8 no. 8 (2013), pp. e71582 [doi] [abs].
- SE McGaugh, CSS Heil, B Manzano-Winkler, L Loewe, S Goldstein, TL Himmel, MAF Noor, Recombination modulates how selection affects linked sites in Drosophila., PLoS Biology, vol. 10 no. 11 (November, 2012), pp. e1001422 [doi] [abs].
- KB Hoehn, SE McGaugh, MAF Noor, Effects of Premature Termination Codon Polymorphisms in the Drosophila pseudoobscura Subclade., Journal of Molecular Evolution, vol. 75 no. 3-4 (October, 2012), pp. 141-150 [doi] [abs].