James R. MacFall, Adjunct Professor in the Department of Radiology and Biomedical Engineering  


James R. MacFall
Contact Info:
Office Location:  1812C Hosp North
Email Address:   send me a message
Web Page: http://camrd4.mc.duke.edu/camrdwebpages/jrmhome.html

Education:

Ph.D., University of Maryland, College Park, 1976
B.A., Northwestern University, 1967
Research Interests:

MacFall's research centers on application and/or development of image processing and magnetic resonance imaging (MRI) techniques for a variety of biomedical focus areas in psychiatry, oncology, lung disorders and pediatric neurological disorders.

Specialties:

Medical Imaging
Representative Publications   (More Publications)

  1. WD Taylor, Z Zhao, A Ashley-Koch, ME Payne, DC Steffens, RR Krishnan, E Hauser, JR MacFall, Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype., Human brain mapping, vol. 34 no. 2 (February, 2013), pp. 295-303 [doi]  [abs].
  2. OI Craciunescu, DS Yoo, E Cleland, N Muradyan, MD Carroll, JR MacFall, DP Barboriak, DM Brizel, Dynamic contrast-enhanced MRI in head-and-neck cancer: the impact of region of interest selection on the intra- and interpatient variability of pharmacokinetic parameters., International journal of radiation oncology, biology, physics, vol. 82 no. 3 (March, 2012), pp. e345-50 [doi]  [abs].
  3. JT Chi, DE Thrall, C Jiang, S Snyder, D Fels, C Landon, L McCall, L Lan, M Hauck, JR MacFall, BL Viglianti, MW Dewhirst, Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics., Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 17 no. 8 (April, 2011), pp. 2549-60 [doi]  [abs].
  4. WD Taylor, JR Macfall, B Boyd, ME Payne, YI Sheline, RR Krishnan, P Murali Doraiswamy, One-year change in anterior cingulate cortex white matter microstructure: relationship with late-life depression outcomes., The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, vol. 19 no. 1 (January, 2011), pp. 43-52 [doi]  [abs].
  5. CR Wyatt, BJ Soher, JR MacFall, Correction of breathing-induced errors in magnetic resonance thermometry of hyperthermia using multiecho field fitting techniques., Medical physics, vol. 37 no. 12 (December, 2010), pp. 6300-9  [abs].
  6. BJ Soher, C Wyatt, SB Reeder, JR MacFall, Noninvasive temperature mapping with MRI using chemical shift water-fat separation., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 63 no. 5 (May, 2010), pp. 1238-46 [doi]  [abs].
  7. S Benjamin, DR McQuoid, GG Potter, ME Payne, JR MacFall, DC Steffens, WD Taylor, The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression., The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, vol. 18 no. 4 (April, 2010), pp. 323-31 [doi]  [abs].
  8. YI Sheline, CF Pieper, DM Barch, K Welsh-Bohmer, K Welsh-Boehmer, RC McKinstry, JR MacFall, G D'Angelo, KS Garcia, K Gersing, C Wilkins, W Taylor, DC Steffens, RR Krishnan, PM Doraiswamy, Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial., Archives of general psychiatry, vol. 67 no. 3 (March, 2010), pp. 277-85 [doi]  [abs].
  9. OI Craciunescu, PR Stauffer, BJ Soher, CR Wyatt, O Arabe, P Maccarini, SK Das, KS Cheng, TZ Wong, EL Jones, MW Dewhirst, Z Vujaskovic, JR MacFall, Accuracy of real time noninvasive temperature measurements using magnetic resonance thermal imaging in patients treated for high grade extremity soft tissue sarcomas., Medical physics, vol. 36 no. 11 (November, 2009), pp. 4848-58  [abs].
  10. HC Hazlett, MD Poe, AA Lightbody, G Gerig, JR Macfall, AK Ross, J Provenzale, A Martin, AL Reiss, J Piven, Teasing apart the heterogeneity of autism: Same behavior, different brains in toddlers with fragile X syndrome and autism., Journal of neurodevelopmental disorders, vol. 1 no. 1 (March, 2009), pp. 81-90 [doi]  [abs].
  11. OI Craciunescu, KL Blackwell, EL Jones, JR Macfall, D Yu, Z Vujaskovic, TZ Wong, V Liotcheva, EL Rosen, LR Prosnitz, TV Samulski, MW Dewhirst, DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study., International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, vol. 25 no. 6 (2009), pp. 405-15 [doi]  [abs].
  12. KW Kim, JR MacFall, ME Payne, Classification of white matter lesions on magnetic resonance imaging in elderly persons., Biological psychiatry, vol. 64 no. 4 (August, 2008), pp. 273-80 [doi]  [abs].
  13. DP Barboriak, JR MacFall, BL Viglianti, MW Dewhirst Dvm, Comparison of three physiologically-based pharmacokinetic models for the prediction of contrast agent distribution measured by dynamic MR imaging., Journal of magnetic resonance imaging : JMRI, vol. 27 no. 6 (June, 2008), pp. 1388-98 [doi]  [abs].
  14. Z Zhao, WD Taylor, M Styner, DC Steffens, KR Krishnan, JR MacFall, Hippocampus shape analysis and late-life depression., PloS one, vol. 3 no. 3 (2008), pp. e1837 [doi]  [abs].
  15. WD Taylor, JR Macfall, ME Payne, DR McQuoid, DC Steffens, JM Provenzale, KR Krishnan, Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms., Psychological medicine, vol. 37 no. 12 (December, 2007), pp. 1763-73 [doi]  [abs].
  16. JR MacFall, BJ Soher, From the RSNA refresher courses: MR imaging in hyperthermia., Radiographics : a review publication of the Radiological Society of North America, Inc, vol. 27 no. 6 (January, 2008), pp. 1809-18 [doi]  [abs].
  17. WD Taylor, JR MacFall, G Gerig, RR Krishnan, Structural integrity of the uncinate fasciculus in geriatric depression: Relationship with age of onset., Neuropsychiatric disease and treatment, vol. 3 no. 5 (2007), pp. 669-74  [abs].
  18. JN Bae, JR MacFall, KR Krishnan, ME Payne, DC Steffens, WD Taylor, Dorsolateral prefrontal cortex and anterior cingulate cortex white matter alterations in late-life depression., Biological psychiatry, vol. 60 no. 12 (December, 2006), pp. 1356-63 [doi]  [abs].
  19. BL Viglianti, AM Ponce, CR Michelich, D Yu, SA Abraham, L Sanders, PS Yarmolenko, T Schroeder, JR MacFall, DP Barboriak, OM Colvin, MB Bally, MW Dewhirst, Chemodosimetry of in vivo tumor liposomal drug concentration using MRI., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 56 no. 5 (November, 2006), pp. 1011-8 [doi]  [abs].
  20. CR Michelich, AW Song, JR Macfall, Dependence of gradient-echo and spin-echo BOLD fMRI at 4 T on diffusion weighting., NMR in biomedicine, vol. 19 no. 5 (August, 2006), pp. 566-72 [doi]  [abs].
  21. JR MacFall, WD Taylor, DE Rex, S Pieper, ME Payne, DR McQuoid, DC Steffens, R Kikinis, AW Toga, KR Krishnan, Lobar distribution of lesion volumes in late-life depression: the Biomedical Informatics Research Network (BIRN)., Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol. 31 no. 7 (July, 2006), pp. 1500-7 [doi]  [abs].
  22. WD Taylor, JR MacFall, ME Payne, DR McQuoid, DC Steffens, JM Provenzale, RR Krishnan, Greater MRI lesion volumes in elderly depressed subjects than in control subjects., Psychiatry research, vol. 139 no. 1 (May, 2005), pp. 1-7 [doi]  [abs].
  23. WD Taylor, JR MacFall, ME Payne, DR McQuoid, JM Provenzale, DC Steffens, KR Krishnan, Late-life depression and microstructural abnormalities in dorsolateral prefrontal cortex white matter., The American journal of psychiatry, vol. 161 no. 7 (July, 2004), pp. 1293-6  [abs].
  24. BL Viglianti, SA Abraham, CR Michelich, PS Yarmolenko, JR MacFall, MB Bally, MW Dewhirst, In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 51 no. 6 (June, 2004), pp. 1153-62 [doi]  [abs].
  25. WD Taylor, E Hsu, KR Krishnan, JR MacFall, Diffusion tensor imaging: background, potential, and utility in psychiatric research., Biological psychiatry, vol. 55 no. 3 (February, 2004), pp. 201-7  [abs].
  26. WD Taylor, JR MacFall, JM Provenzale, ME Payne, DR McQuoid, DC Steffens, KR Krishnan, Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: correlation with vascular risk factors., AJR. American journal of roentgenology, vol. 181 no. 2 (August, 2003), pp. 571-6 [doi]  [abs].
  27. WD Taylor, JR MacFall, DC Steffens, ME Payne, JM Provenzale, KR Krishnan, Localization of age-associated white matter hyperintensities in late-life depression., Progress in neuro-psychopharmacology & biological psychiatry, vol. 27 no. 3 (May, 2003), pp. 539-44 [doi]  [abs].
  28. MH Hsieh, DR McQuoid, RM Levy, ME Payne, JR MacFall, DC Steffens, Hippocampal volume and antidepressant response in geriatric depression., International journal of geriatric psychiatry, vol. 17 no. 6 (June, 2002), pp. 519-25 [doi]  [abs].
  29. AC Guo, JR MacFall, JM Provenzale, Multiple sclerosis: diffusion tensor MR imaging for evaluation of normal-appearing white matter., Radiology, vol. 222 no. 3 (March, 2002), pp. 729-36  [abs].
  30. DV Lewis, DP Barboriak, JR MacFall, JM Provenzale, TV Mitchell, KE VanLandingham, Do prolonged febrile seizures produce medial temporal sclerosis? Hypotheses, MRI evidence and unanswered questions., Progress in brain research, vol. 135 (2002), pp. 263-78  [abs].
  31. DC Steffens, HB Bosworth, JM Provenzale, JR MacFall, Subcortical white matter lesions and functional impairment in geriatric depression., Depression and anxiety, vol. 15 no. 1 (2002), pp. 23-8  [abs].
  32. JR MacFall, ME Payne, JE Provenzale, KR Krishnan, Medial orbital frontal lesions in late-onset depression., Biological psychiatry, vol. 49 no. 9 (May, 2001), pp. 803-6  [abs].
  33. ST Engelter, JM Provenzale, JR Petrella, DM DeLong, JR MacFall, The effect of aging on the apparent diffusion coefficient of normal-appearing white matter., AJR. American journal of roentgenology, vol. 175 no. 2 (August, 2000), pp. 425-30 [doi]  [abs].
  34. YH Kao, JR MacFall, Correction of MR kappa-space data corrupted by spike noise., IEEE transactions on medical imaging, vol. 19 no. 7 (July, 2000), pp. 671-80  [abs].
  35. OI Craciunescu, TV Samulski, JR MacFall, ST Clegg, Perturbations in hyperthermia temperature distributions associated with counter-current flow: numerical simulations and empirical verification., IEEE transactions on bio-medical engineering, vol. 47 no. 4 (April, 2000), pp. 435-43 [doi]  [abs].
  36. Z Vujaskovic, JM Poulson, AA Gaskin, DE Thrall, RL Page, HC Charles, JR MacFall, DM Brizel, RE Meyer, DM Prescott, TV Samulski, MW Dewhirst, Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment., International journal of radiation oncology, biology, physics, vol. 46 no. 1 (January, 2000), pp. 179-85  [abs].
  37. DP Barboriak, JM Provenzale, JR MacFall, White matter lesion contrast in fast spin-echo fluid-attenuated inversion recovery imaging: effect of varying effective echo time and echo train length., AJR. American journal of roentgenology, UNITED STATES, vol. 173 no. 4 (October, 1999), pp. 1091-6  [abs].
  38. LF Donnelly, JR MacFall, HP McAdams, JM Majure, J Smith, DP Frush, P Bogonad, HC Charles, CE Ravin, Cystic fibrosis: combined hyperpolarized 3He-enhanced and conventional proton MR imaging in the lung--preliminary observations., Radiology, vol. 212 no. 3 (September, 1999), pp. 885-9  [abs].
  39. EW Hsu, LW Hedlund, JR MacFall, Functional MRI of the rat somatosensory cortex: effects of hyperventilation., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, UNITED STATES, vol. 40 no. 3 (September, 1998), pp. 421-6  [abs].
  40. EW Hsu, SB Reeder, JR MacFall, Single-shot, variable flip-angle slice-selective excitation with four gradient-modulated adiabatic half-passage segments., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, UNITED STATES, vol. 40 no. 2 (August, 1998), pp. 334-40  [abs].
  41. YH Kao, X Wan, JR MacFall, Simultaneous multislice acquisition with arterial-flow tagging (SMART) using echo planar imaging (EPI)., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 39 no. 4 (April, 1998), pp. 662-5  [abs].
  42. DL Carter, JR MacFall, ST Clegg, X Wan, DM Prescott, HC Charles, TV Samulski, Magnetic resonance thermometry during hyperthermia for human high-grade sarcoma., International journal of radiation oncology, biology, physics, vol. 40 no. 4 (March, 1998), pp. 815-22  [abs].
  43. JP Vallée, HD Sostman, JR MacFall, T Wheeler, LW Hedlund, CE Spritzer, RE Coleman, MRI quantitative myocardial perfusion with compartmental analysis: a rest and stress study., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, UNITED STATES, vol. 38 no. 6 (December, 1997), pp. 981-9  [abs].
  44. JR MacFall, DM Prescott, HC Charles, TV Samulski, 1H MRI phase thermometry in vivo in canine brain, muscle, and tumor tissue., Medical physics, vol. 23 no. 10 (October, 1996), pp. 1775-82  [abs].
  45. JR MacFall, HC Charles, RD Black, H Middleton, JC Swartz, B Saam, B Driehuys, C Erickson, W Happer, GD Cates, GA Johnson, CE Ravin, Human lung air spaces: potential for MR imaging with hyperpolarized He-3., Radiology, vol. 200 no. 2 (August, 1996), pp. 553-8  [abs].
  46. MacFall JR, Prescott DM, Fuller E, Samulski TV. Temperature Dependence of Canine Brain Tissue Diffusion Coefficient Measured In Vivo with Magnetic Resonance Echo-Planar Imaging. International Journal of Hyperthemia 1995; 11:73-86 .
  47. JR MacFall, CE Byrum, I Parashos, B Early, HC Charles, V Chittilla, OB Boyko, L Upchurch, KR Krishnan, Relative accuracy and reproducibility of regional MRI brain volumes for point-counting methods., Psychiatry research, vol. 55 no. 3 (September, 1994), pp. 167-77  [abs].
  48. MacFall JR, Boyko O, Charles HC, Byrum C, Chittilla V, Parashos I, Upchurch L, Krishnan R: Relative Accuracy and Reproducibility of Regional MRI Brain Volume for Point Counting Methods. Psychiatry Research, 1994; 55:167-177. .
  49. JJ Wu, JR MacFall, HD Sostman, LW Hedlund, Clot-blood contrast in fast gradient-echo magnetic resonance imaging., Investigative radiology, vol. 28 no. 7 (July, 1993), pp. 586-93  [abs].
  50. TK Foo, JR MacFall, HD Sostman, CE Hayes, Single-breath-hold venous or arterial flow-suppressed pulmonary vascular MR imaging with phased-array coils., Journal of magnetic resonance imaging : JMRI, vol. 3 no. 4 (September, 1993), pp. 611-6  [abs].
  51. TK Foo, JR MacFall, CE Hayes, HD Sostman, BE Slayman, Pulmonary vasculature: single breath-hold MR imaging with phased-array coils., Radiology, vol. 183 no. 2 (May, 1992), pp. 473-7  [abs].
  52. JR MacFall, HD Sostman, TK Foo, Thick-section, single breath-hold magnetic resonance pulmonary angiography., Investigative radiology, vol. 27 no. 4 (April, 1992), pp. 318-22  [abs].
  53. HD Sostman, DT Layish, VF Tapson, CE Spritzer, DM DeLong, P Trotter, JR MacFall, EF Patz, PC Goodman, PK Woodard, TK Foo, JL Farber, Prospective comparison of helical CT and MR imaging in clinically suspected acute pulmonary embolism., Journal of magnetic resonance imaging : JMRI, UNITED STATES, vol. 6 no. 2 , pp. 275-81  [abs].
  54. JP Vallée, HD Sostman, JR MacFall, RE Coleman, Quantification of myocardial perfusion with MRI and exogenous contrast agents., Cardiology, SWITZERLAND, vol. 88 no. 1 , pp. 90-105  [abs].