Publications [#260281] of Daniel Rittschof
search PubMed.Papers Published
- Schoenfeld, RC; Conova, S; Rittschof, D; Ganem, B, Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.,
Bioorganic & medicinal chemistry letters, vol. 12 no. 5
(March, 2002),
pp. 823-825 [11859011], [doi] .
(last updated on 2024/08/25)Abstract:
Synthesis and biological evaluation of two naturally-occurring bromotyramines, moloka'iamine 1 and 3,5-dibromo-4-methoxy-beta-phenethylamine 2, together with several analogues, have been completed. Bromotyramine 2 is cytotoxic, and was found to be a potent antifoulant. Analogues 15 and 16 also displayed significant cytotoxic and antifouling activities.