Center for Biomolecular and Tissue Engineering Center for Biomolecular and Tissue Engineering
Pratt School of Engineering
Duke University
 HOME > pratt > CBTE    Search Help Login 

Publications of Christopher D. Kontos    :chronological  alphabetical  combined  bibtex listing:

Papers Published

  1. AJ Simnick, M Amiram, W Liu, G Hanna, MW Dewhirst, CD Kontos, A Chilkoti, In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide., Journal of controlled release : official journal of the Controlled Release Society, vol. 155 no. 2 (October, 2011), pp. 144-51, ISSN 1873-4995 [doi]  [abs]
  2. L Chen, B Xu, L Liu, Y Luo, H Zhou, W Chen, T Shen, X Han, CD Kontos, S Huang, Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death., Free radical biology & medicine, vol. 50 no. 5 (March, 2011), pp. 624-32, ISSN 1873-4596 [doi]  [abs]
  3. FT Wu, MO Stefanini, F Mac Gabhann, CD Kontos, BH Annex, AS Popel, VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model., American journal of physiology. Heart and circulatory physiology, vol. 298 no. 6 (June, 2010), pp. H2174-91, ISSN 1522-1539 [doi]  [abs]
  4. SB Furgeson, PA Simpson, I Park, V Vanputten, H Horita, CD Kontos, RA Nemenoff, MC Weiser-Evans, Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation., Cardiovascular research, vol. 86 no. 2 (May, 2010), pp. 274-82, ISSN 1755-3245 [doi]  [abs]
  5. FT Wu, MO Stefanini, F Mac Gabhann, CD Kontos, BH Annex, AS Popel, A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use., Journal of cellular and molecular medicine, vol. 14 no. 3 (March, 2010), pp. 528-52, ISSN 1582-4934 [doi]  [abs]
  6. RL Sagana, M Yan, AM Cornett, JL Tsui, DA Stephenson, SK Huang, BB Moore, MN Ballinger, J Melonakos, CD Kontos, DM Aronoff, M Peters-Golden, ES White, Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression., The Journal of biological chemistry, vol. 284 no. 47 (November, 2009), pp. 32264-71, ISSN 1083-351X [doi]  [abs]
  7. A Ahmed, T Fujisawa, XL Niu, S Ahmad, B Al-Ani, K Chudasama, A Abbas, R Potluri, V Bhandari, CM Findley, GK Lam, J Huang, PW Hewett, M Cudmore, CD Kontos, Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide., Circulation research, vol. 104 no. 12 (June, 2009), pp. 1333-6, ISSN 1524-4571 [doi]  [abs]
  8. FT Wu, MO Stefanini, FM Gabhann, CD Kontos, BH Annex, AS Popel, Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport., Physiological genomics, United States, vol. 38 no. 1 (June, 2009), pp. 29-41, ISSN 1531-2267  [abs]
  9. B Lima, GK Lam, L Xie, DL Diesen, N Villamizar, J Nienaber, E Messina, D Bowles, CD Kontos, JM Hare, JS Stamler, HA Rockman, Endogenous S-nitrosothiols protect against myocardial injury., Proceedings of the National Academy of Sciences of the United States of America, United States, vol. 106 no. 15 (April, 2009), pp. 6297-302, ISSN 1091-6490  [abs]
  10. W Qiu, L Federico, M Naples, RK Avramoglu, R Meshkani, J Zhang, J Tsai, M Hussain, K Dai, J Iqbal, CD Kontos, Y Horie, A Suzuki, K Adeli, Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins., Hepatology (Baltimore, Md.), United States, vol. 48 no. 6 (December, 2008), pp. 1799-809, ISSN 1527-3350  [abs]
  11. R Estrada, Q Zeng, H Lu, H Sarojini, JF Lee, SP Mathis, T Sanchez, E Wang, CD Kontos, CY Lin, T Hla, B Haribabu, MJ Lee, Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells., The Journal of biological chemistry, United States, vol. 283 no. 44 (October, 2008), pp. 30363-75, ISSN 0021-9258  [abs]
  12. D Xie, CM Findley, JM Greenfield, AM Pippen, CD Kontos, CF Donatucci, BH Annex, A VEGF trap inhibits the beneficial effect of bFGF on vasoreactivity in corporal tissues of hypercholesterolemic rabbits., The journal of sexual medicine, vol. 5 no. 9 (September, 2008), pp. 2069-78, ISSN 1743-6109 [doi]  [abs]
  13. CM Findley, RG Mitchell, BD Duscha, BH Annex, CD Kontos, Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease., Journal of the American College of Cardiology, vol. 52 no. 5 (July, 2008), pp. 387-93, ISSN 1558-3597 [doi]  [abs]
  14. D Xie, S Hazarika, AJ Andrich, ME Padgett, CD Kontos, CF Donatucci, BH Annex, High cholesterol feeding in C57/Blc6 mice alters expression within the VEGF receptor-ligand family in corporal tissue., The journal of sexual medicine, United States, vol. 5 no. 5 (May, 2008), pp. 1137-48, ISSN 1743-6109  [abs]
  15. RR White, JA Roy, KD Viles, BA Sullenger, CD Kontos, A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated Tie2 activation and function., Angiogenesis, vol. 11 no. 4 (2008), pp. 395-401, ISSN 1573-7209 [doi]  [abs]
  16. CM Findley, MJ Cudmore, A Ahmed, CD Kontos, VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling., Arteriosclerosis, thrombosis, and vascular biology, vol. 27 no. 12 (December, 2007), pp. 2619-26, ISSN 1524-4636 [doi]  [abs]
  17. S Hazarika, AO Dokun, Y Li, AS Popel, CD Kontos, BH Annex, Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1., Circulation research, vol. 101 no. 9 (October, 2007), pp. 948-56, ISSN 1524-4571 [doi]  [abs]
  18. J Mi, X Zhang, ZN Rabbani, Y Liu, SK Reddy, Z Su, FK Salahuddin, K Viles, PH Giangrande, MW Dewhirst, BA Sullenger, CD Kontos, BM Clary, RNA Aptamer-targeted Inhibition of NF-kappaB Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin., Mol Ther (October, 2007), ISSN 1525-0016  [abs]
  19. S Sarraf-Yazdi, J Mi, BJ Moeller, X Niu, RR White, CD Kontos, BA Sullenger, MW Dewhirst, BM Clary, Inhibition of In Vivo Tumor Angiogenesis and Growth Via Systemic Delivery of an Angiopoietin 2-specific RNA Aptamer., J Surg Res (October, 2007), ISSN 0022-4804  [abs]
  20. CD Kontos, BH Annex, Engineered transcription factors for therapeutic angiogenesis., Current opinion in molecular therapeutics, vol. 9 no. 2 (April, 2007), pp. 145-52, ISSN 1464-8431  [abs]
  21. Y Cao, P Sonveaux, S Liu, Y Zhao, J Mi, BM Clary, CY Li, CD Kontos, MW Dewhirst, Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth., Cancer research, United States, vol. 67 no. 8 (April, 2007), pp. 3835-44, ISSN 0008-5472  [abs]
  22. Y Li, S Hazarika, D Xie, AM Pippen, CD Kontos, BH Annex, In mice with type 2 diabetes, a vascular endothelial growth factor (VEGF)-activating transcription factor modulates VEGF signaling and induces therapeutic angiogenesis after hindlimb ischemia., Diabetes, vol. 56 no. 3 (March, 2007), pp. 656-65, ISSN 0012-1797 [doi]  [abs]
  23. R DeKroon, JB Robinette, AB Hjelmeland, E Wiggins, M Blackwell, M Mihovilovic, M Fujii, J York, J Hart, C Kontos, J Rich, WJ Strittmatter, APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2., Circulation research, United States, vol. 99 no. 8 (October, 2006), pp. 829-36, ISSN 1524-4571  [abs]
  24. D Xie, Y Li, EA Reed, SI Odronic, CD Kontos, BH Annex, An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia., Journal of vascular surgery, vol. 44 no. 1 (July, 2006), pp. 166-75, ISSN 0741-5214 [doi]  [abs]
  25. N Huang, A Khan, H Ashrafpour, PC Neligan, CR Forrest, CD Kontos, CY Pang, Efficacy and mechanism of adenovirus-mediated VEGF-165 gene therapy for augmentation of skin flap viability., American journal of physiology. Heart and circulatory physiology, United States, vol. 291 no. 1 (July, 2006), pp. H127-37, ISSN 0363-6135  [abs]
  26. J Mi, S Sarraf-Yazdi, X Zhang, Y Cao, MW Dewhirst, CD Kontos, CY Li, BM Clary, A comparison of antiangiogenic therapies for the prevention of liver metastases., The Journal of surgical research, United States, vol. 131 no. 1 (March, 2006), pp. 97-104, ISSN 0022-4804  [abs]
  27. ES White, RG Atrasz, B Hu, SH Phan, V Stambolic, TW Mak, CM Hogaboam, KR Flaherty, FJ Martinez, CD Kontos, GB Toews, Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10)., American journal of respiratory and critical care medicine, vol. 173 no. 1 (January, 2006), pp. 112-21, ISSN 1073-449X [doi]  [abs]
  28. J Mi, X Zhang, ZN Rabbani, Y Liu, Z Su, Z Vujaskovic, CD Kontos, BA Sullenger, BM Clary, H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high-level inhibition of intracellular protein activity., Nucleic acids research, England, vol. 34 no. 12 (2006), pp. 3577-84, ISSN 1362-4962  [abs]
  29. AB Hjelmeland, MD Hjelmeland, Q Shi, JL Hart, DD Bigner, XF Wang, CD Kontos, JN Rich, Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity., Cancer research, United States, vol. 65 no. 24 (December, 2005), pp. 11276-81, ISSN 0008-5472  [abs]
  30. D Xie, CD Kontos, CF Donatucci, BH Annex, Cholesterol feeding reduces vascular endothelial growth factor signaling in rabbit corporal tissues., The journal of sexual medicine, United States, vol. 2 no. 5 (September, 2005), pp. 634-40, ISSN 1743-6095  [abs]
  31. S Liu, RT Premont, CD Kontos, S Zhu, DC Rockey, A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension., Nature medicine, vol. 11 no. 9 (September, 2005), pp. 952-8, ISSN 1078-8956 [doi]  [abs]
  32. JA Hata, JA Petrofski, JN Schroder, ML Williams, SH Timberlake, A Pippen, MT Corwin, AK Solan, A Jakoi, TR Gehrig, CD Kontos, CA Milano, Modulation of phosphatidylinositol 3-kinase signaling reduces intimal hyperplasia in aortocoronary saphenous vein grafts., The Journal of thoracic and cardiovascular surgery, vol. 129 no. 6 (June, 2005), pp. 1405-13, ISSN 0022-5223 [doi]  [abs]
  33. N Singh, E Macnamara, S Rashid, J Ambati, CD Kontos, E Higgins, BK Ambati, Systemic soluble Tie2 expression inhibits and regresses corneal neovascularization., Biochemical and biophysical research communications, United States, vol. 332 no. 1 (June, 2005), pp. 194-9, ISSN 0006-291X  [abs]
  34. T Sanchez, S Thangada, MT Wu, CD Kontos, D Wu, H Wu, T Hla, PTEN as an effector in the signaling of antimigratory G protein-coupled receptor., Proceedings of the National Academy of Sciences of the United States of America, United States, vol. 102 no. 12 (March, 2005), pp. 4312-7, ISSN 0027-8424  [abs]
  35. J Huang, XL Niu, AM Pippen, BH Annex, CD Kontos, Adenovirus-mediated intraarterial delivery of PTEN inhibits neointimal hyperplasia., Arteriosclerosis, thrombosis, and vascular biology, vol. 25 no. 2 (February, 2005), pp. 354-8, ISSN 1524-4636 [doi]  [abs]
  36. A Khan, H Ashrafpour, N Huang, PC Neligan, C Kontos, A Zhong, CR Forrest, CY Pang, Acute local subcutaneous VEGF165 injection for augmentation of skin flap viability: efficacy and mechanism., American journal of physiology. Regulatory, integrative and comparative physiology, United States, vol. 287 no. 5 (November, 2004), pp. R1219-29, ISSN 0363-6119  [abs]
  37. Q Dai, J Huang, B Klitzman, C Dong, PJ Goldschmidt-Clermont, KL March, J Rokovich, B Johnstone, EJ Rebar, SK Spratt, CC Case, CD Kontos, BH Annex, Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia., Circulation, vol. 110 no. 16 (October, 2004), pp. 2467-75, ISSN 1524-4539 [doi]  [abs]
  38. M Yamaoka-Tojo, M Ushio-Fukai, L Hilenski, SI Dikalov, YE Chen, T Tojo, T Fukai, M Fujimoto, NA Patrushev, N Wang, CD Kontos, GS Bloom, RW Alexander, IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation., Circulation research, United States, vol. 95 no. 3 (August, 2004), pp. 276-83, ISSN 1524-4571  [abs]
  39. S Shan, ND Robson, Y Cao, T Qiao, CY Li, CD Kontos, M Garcia-Blanco, MW Dewhirst, Responses of vascular endothelial cells to angiogenic signaling are important for tumor cell survival., The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, United States, vol. 18 no. 2 (February, 2004), pp. 326-8, ISSN 1530-6860  [abs]
  40. G Zadeh, B Qian, A Okhowat, N Sabha, CD Kontos, A Guha, Targeting the Tie2/Tek receptor in astrocytomas., The American journal of pathology, United States, vol. 164 no. 2 (February, 2004), pp. 467-76, ISSN 0002-9440  [abs]
  41. KG Peters, CD Kontos, PC Lin, AL Wong, P Rao, L Huang, MW Dewhirst, S Sankar, Functional significance of Tie2 signaling in the adult vasculature., Recent progress in hormone research, vol. 59 (2004), pp. 51-71, ISSN 0079-9963  [abs]
  42. J Cai, S Ahmad, WG Jiang, J Huang, CD Kontos, M Boulton, A Ahmed, Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells., Diabetes, United States, vol. 52 no. 12 (December, 2003), pp. 2959-68, ISSN 0012-1797  [abs]
  43. S Liu, RT Premont, CD Kontos, J Huang, DC Rockey, Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt., The Journal of biological chemistry, United States, vol. 278 no. 50 (December, 2003), pp. 49929-35, ISSN 0021-9258  [abs]
  44. RR White, S Shan, CP Rusconi, G Shetty, MW Dewhirst, CD Kontos, BA Sullenger, Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2., Proceedings of the National Academy of Sciences of the United States of America, vol. 100 no. 9 (April, 2003), pp. 5028-33, ISSN 0027-8424 [doi]  [abs]
  45. XL Niu, KG Peters, CD Kontos, Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism., The Journal of biological chemistry, vol. 277 no. 35 (August, 2002), pp. 31768-73, ISSN 0021-9258 [doi]  [abs]
  46. J Huang, CD Kontos, Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN., Arteriosclerosis, thrombosis, and vascular biology, United States, vol. 22 no. 5 (May, 2002), pp. 745-51, ISSN 1524-4636  [abs]
  47. J Huang, CD Kontos, PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects., The Journal of biological chemistry, vol. 277 no. 13 (March, 2002), pp. 10760-6, ISSN 0021-9258 [doi]  [abs]
  48. CD Kontos, EH Cha, JD York, KG Peters, The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis., Molecular and cellular biology, vol. 22 no. 6 (March, 2002), pp. 1704-13, ISSN 0270-7306  [abs]
  49. B Bussolati, C Dunk, M Grohman, CD Kontos, J Mason, A Ahmed, Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide., The American journal of pathology, United States, vol. 159 no. 3 (September, 2001), pp. 993-1008, ISSN 0002-9440  [abs]
  50. L Huang, S Sankar, C Lin, CD Kontos, AD Schroff, EH Cha, SM Feng, SF Li, Z Yu, RL Van Etten, MA Blanar, KG Peters, HCPTPA, a protein tyrosine phosphatase that regulates vascular endothelial growth factor receptor-mediated signal transduction and biological activity., The Journal of biological chemistry, UNITED STATES, vol. 274 no. 53 (December, 1999), pp. 38183-8, ISSN 0021-9258  [abs]
  51. CD Kontos, BH Annex, Angiogenesis., Current atherosclerosis reports, United States, vol. 1 no. 2 (September, 1999), pp. 165-71, ISSN 1523-3804  [abs]
  52. JT Calvert, TJ Riney, CD Kontos, EH Cha, VG Prieto, CR Shea, JN Berg, NC Nevin, SA Simpson, KA Pasyk, MC Speer, KG Peters, DA Marchuk, Allelic and locus heterogeneity in inherited venous malformations., Human molecular genetics, ENGLAND, vol. 8 no. 7 (July, 1999), pp. 1279-89, ISSN 0964-6906  [abs]
  53. CD Kontos, TP Stauffer, WP Yang, JD York, L Huang, MA Blanar, T Meyer, KG Peters, Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt., Molecular and cellular biology, vol. 18 no. 7 (July, 1998), pp. 4131-40, ISSN 0270-7306  [abs]
  54. KG Peters, A Coogan, D Berry, J Marks, JD Iglehart, CD Kontos, P Rao, S Sankar, E Trogan, Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis., British journal of cancer, SCOTLAND, vol. 77 no. 1 (1998), pp. 51-6, ISSN 0007-0920  [abs]
  55. CD Kontos, EP Wei, JI Williams, HA Kontos, JT Povlishock, Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo., The American journal of physiology, UNITED STATES, vol. 263 no. 4 Pt 2 (October, 1992), pp. H1234-42, ISSN 0002-9513  [abs]
Duke University * Pratt * CBTE * Reload * Login
x